Words similar to activator
Example sentences for: activator
How can you use “activator” in a sentence? Here are some example sentences to help you improve your vocabulary:
For example, KIF17a, a member of the N-4 subgroup that is predominantly expressed in germ cells, was recently shown to possess transcriptional regulatory properties by controlling access of the transcriptional activator protein CREM to a coactivator, ACT [ 37 ] . Clearly, functional analysis of the KIF27 polypeptide will be needed to determine the subcellular location of this protein to determine whether it may add to the growing number of kinesins that function in the nucleus.
15d-PGJ 2 , 15-deoxy-delta 12, 14-PGJ 2 ; AP-1, activator protein-1; ERK, p42/44, Extracellular signal-Regulated Kinase; LDL, low density lipoprotein; MAP kinases, Mitogen-Activated Protein kinases; MTT (3-(4,5-dimethylthiazole-2yl)-2,5-diphenyltetrazolium bromide); PCD, programmed cell death; PPARs, peroxisome proliferator-activated receptors; SAPK/JNK, Stress-Activated Protein Kinase/ c-Jun NH2-terminal Kinase.
This demonstrates that NFATp is a bona fide transcriptional activator.
Initial results showed that CAR is an apparently constitutive transactivator able to activate gene expression in the absence of exogenously added ligands [ 8 9 ] . The first CAR ligands identified, androstanol and androstenol, are inverse agonists that block this constitutive transactivation [ 10 ] . More recently, it has been found that CAR mediates the characteristic response of a subset of drug metabolizing enzymes to a variety of structurally unrelated foreign compounds [ 11 ] . These xenobiotic activators are referred to as "phenobarbital (PB) - like," based on the prototypic effects of the anti-epileptic agent on drug metabolism [ 12 13 14 ] . The most potent activator of murine CAR is the high affinity agonist ligand TCPOBOP (1,4-bis [2-(3,5-dichloropyridyloxy)]benzene) [ 15 16 ] .
Together, these results suggest that translation of the +1 frame of GFP, after the random peptide insert, results in a molecule with activator properties.
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