Example sentences for: activator

How can you use “activator” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • One involved identification of a non-peptide activator of the granulocyte colony-stimulating factor (GCSF) pathway that appeared to act via receptor oligomerization [ 18 ] . Another report described a small-molecule activator of the insulin-signaling pathway that also acts at the level of the receptor [ 19 ] .

  • Our finding that recombinant HA-NFATp activates transcription in a reconstituted transcription system provided compelling evidence that NFATp is a bona fide activator.

  • ER = estrogen receptor; HGFA = hepatocyte growth factor activator; HGF/SF = hepatocyte growth factor/scatter factor; PR = progesterone receptor; RT-PCR = reverse transcriptase-polymerase chain reaction.

  • [ 3 ] ) that include tissue plasminogen activator [ 5 ] , reactive oxygen species such as O 2 - [ 6 7 ] , cytokines like TNF-α [ 7 8 ] and proteases, in particular MMP-9 [ 7 9 ] , in a time- and concentration-dependent manner.

  • Aberrant promoter methylation changes that occur in cancer are associated with transcriptional repression and loss of function of the gene by interrupting the binding of proteins involved in transcription activator complex [ 12 ] . Our gene expression analysis by RT-PCR demonstrated that all tumors that showed methylation of MGMT and MLH1 also showed down-regulated expression, while RASSF1A and RARB genes showed down-regulation of mRNA levels in most of the methylated tumors.

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