Example sentences for: activator

How can you use “activator” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Aberrant promoter methylation changes that occur in cancer are associated with transcriptional repression and loss of function of the gene by interrupting the binding of proteins involved in transcription activator complex [ 12 ] . Our gene expression analysis by RT-PCR demonstrated that all tumors that showed methylation of MGMT and MLH1 also showed down-regulated expression, while RASSF1A and RARB genes showed down-regulation of mRNA levels in most of the methylated tumors.

  • 5-HT, acting via the 5-HT 2A receptor, is a known activator of the ERK pathway in vascular smooth muscle cells [ 2 22 ] . In these studies we tested the hypothesis that 5-HT would activate the JNK and p38 pathways in rat aortic vascular smooth muscle cells.

  • AGTII, angiotensin II; BSA, bovine serum albumin; CHX, cycloheximide; CPT, camptothecin; DMSO, dimethyl sulfoxide; FITC, fluorescein isothiocyanate; HBSS, Hanks' balanced salt solution; HUVEC, human umbilical vein endothelial cells; IC-IgG, IgG isotype control; Mab, monoclonal antibody; MP, microparticles; PE, phycoerythrin; PI, propidium iodide; PMA, phorbol-myristate-acetate; PS, phosphatidylserine; TRAP, thrombin receptor activating peptide (SFLLRNP); TNF, tumor necrosis factor; TPA, tissue plasminogen activator; TUNEL, terminal deoxynucleotidyltransferase dUTP nick end labeling; ZVAD, Z-Val-Ala-Asp-fluoromethyl ketone.

  • Phorbol 12-myristate 13-acetate (PMA) is a specific activator of group A and group B protein kinase C. We wanted to determine, therefore, if protein kinase C activation by PMA would enhance the toxicity of CEES.

  • These include urokinase-type plasminogen activator receptor (PLAUR; MIM 173391, see Online Mendelian Inheritance in Man http://www.ncbi.nlm.nih.gov/omim/) [ 44 ] , apolipoproteins E (MIM 107741), CII (MIM 207750) and CI (MIM 107710), human brain-specific Na(+)-dependent inorganic phosphate cotransporter (hBNPI, 19q13) [ 45 ] , cardiac troponin I (TnIc, 19q; MIM 191044) [ 46 47 ] , cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL, caused by mutations in the Notch3 gene, 19q12; MIM 602275) [ 48 ] , isolated cardiac conduction disease (19q13.


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