Words similar to activator
Example sentences for: activator
How can you use “activator” in a sentence? Here are some example sentences to help you improve your vocabulary:
In light of a recent report establishing the tumor suppressor p53 as a transcriptional activator of PTEN expression [ 41 ] , we investigated whether this protein would affect the observed induction of PTEN in our cell system.
The possibility that domoic acid may activate neonatal microglia both in vitro and in vivo is suggested by recent observations with kainic acid, a domoic acid and glutamate analog that can induce upregulation of neonatal microglia scavenger receptor mRNA [ 22 ] and tissue plasminogen activator release [ 23 ] . The putative molecular explanation for these observations has been that kainic acid activates the ionotropic AMPA glutamate GluR4 subunit which has recently been shown to be expressed by activated microglia following transient forebrain ischemia in vivo [ 24 ] . Because this subunit of the AMPA glutamate receptor has affinity for domoic acid [ 25 26 27 ] , we hypothesized that domoic acid might activate neonatal microglia in vitro and lead to concomitant mediator release [ 21 ] .
Specifically, the influence of a potent PKC activator, PMA, and clinically tested drug, Bryostatin 1, on the IFNg-induced MHCII expression in several IFNg-resistant tumor cell lines was examined.
The Hh-signaling pathway comprises three main components: the Hh ligand; a transmembrane receptor circuit composed of the negative regulator Patched (Ptc) plus an activator, Smoothened (Smo); and finally a cytoplasmic complex that regulates the Cubitus interruptus (Ci) or Gli family of transcriptional effectors.
Plasminogen activator inhibitor-1 (PAI-1) is a serine proteinase inhibitor in the serpin superfamily [ 1 2 3 ] . This 50 kDa glycoprotein is apparently the most important physiological inhibitor of tissue-type plasminogen activator (tPA) and of urokinase plasminogen activator (uPA).
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