Example sentences for: activator

How can you use “activator” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • DAG is an activator of certain isozymes of PKC and lysophosphatidic acid acts as an intercellular messenger for many cell types.

  • The potency of IFN-γ as a macrophage activator and osteoclast inhibitor suggests a prominent role for T cells and/or NK cells in the regulation of bone resorption, as these cells constitute the major source of IFN-γ [ 18 ] . A link between activated T cells and osteoclast inhibition by IFN-γ has been highlighted in a report by Takayanagi et al ., providing the first in vivo evidence that the immune system may influence osteoclastogenesis [ 38 ] . Interestingly, other groups have demonstrated that activated T cells induce osteoclastogenesis via upregulation of surface RANKL, presenting a dilemma regarding the role of activated T cells in osteoclastogenesis [ 20 40 45 ] .

  • We also identified 4 indirect regulators of EC activation and angiogenesis, i.e., myeloblastin, cathepsin B, calpastatin, and urokinase plasminogen activator surface receptor (u-PAR).

  • Since the Hh receptor, Ptc, serves to inhibit signaling, a small-molecule pathway activator would need to be capable of one of the following: first, interfering with the inhibitory effect that Ptc exerts on Smo; second, activating Smo without affecting Ptc; or third, activating the pathway downstream of Smo.

  • Specifically, nuclear translocation of NF-κB and mitogen-activated protein kinase (MAPK) stimulation of activator protein-1 (AP-1) are required for transcription of cytokine-induced MMP-1 and MMP-13.


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