Example sentences for: activates

How can you use “activates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, the data suggest that Btk:ER activates JNK by a mechanism that is dependent on PLCγ2, rather than through activation of more downstream elements of the JNK cascade.

  • This may suggest that either the two PKC activators act through different isoforms of PKC or PMA also activates enzymes outside the PKC family such as MAPK [ 18 ] . Whatever the mechanism, it appears possible to restore the IFNg-dependent MHCII expression in LS1034 cell line by clinically acceptable concentrations of Bryostatin 1.

  • Cdc14 subsequently dephosphorylates (and thereby activates) proteins involved in Sic1 expression (Swi5) and C1b degradation (Hct1/Cdh1) [ 19 41 50 ] , thereby eliminating mitotic Cdk activity and promoting exit from mitosis.

  • In contrast, mobility gel-shift analysis revealed that treatment with ISIS 15534 produces a marked increase in the association of GR with GRE-containing DNA, and transient transfection studies employing a GR-responsive reporter plasmid revealed that the suppression of PP5 expression activates GR-dependent transcription in the absence of hormone [ 25].

  • PMA, a phorbol ester, activates PKC and has previously been shown to activate SL-1 [ 40 ] . It appears that mesothelin is activated by Wnt-1, which can be mimicked by LiCl, and that SL-1 is activated by Wnt-5a in a beta-catenin-independent manner, which can be mimicked by activating PKC.


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