Example sentences for: activate

How can you use “activate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We focused on two genes, mesothelin and SL-1, whose regulation by Wnts was reproducible using a variety of methods to activate the Wnt signaling pathways.

  • Phenobarbitol and phenobarbitol-like substances activate CAR-RXR heterodimers (CAR, constitutive androstane receptor), that bind DR-4 response elements on the Cyp 2 promoter.

  • Several vasoactive G-protein coupled agonists, including angiotensin II and endothelin, have also been shown to activate the ERK pathway in vascular smooth muscle cells [ 6 21 ] . These same hormones also activate the JNK and p38 pathways.

  • Even though H 2 O 2 did not increase PPARγ protein expression significantly as indicated in the previous study, experiments were performed to determine whether PPARγ agonists could activate the existing PPARγ thus preventing H 2 O 2 induced cytotoxicity in RPE cells.

  • Still, other reports, have suggested that opioid ligands with agonistic effect at μ opioid receptors and antagonistic effect at δ opioid receptors are potentially useful analgesics [ 3 17 18 ] . These latter results advocate that the key to designing opioid ligands with optimal analgesia and minimal side effects may be in the design of ligands that act on more than one receptor type, but activate each receptor differently.


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