Example sentences for: activate

How can you use “activate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Whether sulfur transferase functionality is retained in the rhodanese-like domains of MoeBR and MoeZ and whether these proteins can function to activate a substrate as well as transfer a sulfur-containing moiety is unknown.

  • The reaction was incubated at 37°C for 5 min to digest RNA, followed by 94°C for 2 min to activate the Advantage™ cDNA polymerase, 65°C for 1 min to prime and 75°C for 30 min to extend the second strand cDNA.

  • For example, IL-6 acting via its receptor has been shown to activate STAT3 in LNCaP cells.

  • Although MHCII are not expressed by the vast majority of studied mouse and human tumors, CD4+ T lymphocytes specific to MHCII-restricted tumor antigens have been found in various cancers [ 1 ] . Those lymphocytes are believed to be generated in vivo following the recognition of MHCII-tumor peptide complexes expressed by host antigen presenting cells and can cause regression of MHCII-negative tumors indirectly, via secretion of cytokines such as IL-2 or IFNg [ 2 ] . The released cytokines can recruit and activate cytotoxic CD8+ T lymphocytes and/or accessory cells (eosinophills, macrophages) which further mediate tumor destruction.

  • Having determined that our domoic acid preparation was stable and undegraded, that rat neonatal microglia expressed GluR4 in vitro and that 1 mM domoic acid was toxic to cerebellar granule neurons in vitro but did not affect the viability of rat neonatal microglia, we then investigated whether a short term 1-6 hour exposure to 1 mM domoic acid would activate rat neonatal microglia in vitro.


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