Words similar to activate
Example sentences for: activate
How can you use “activate” in a sentence? Here are some example sentences to help you improve your vocabulary:
In comparison to the two general alternative mechanisms utilized by known transforming viruses to promote cell-cycle progression, namely, by activating or bypassing endogenous D-type cyclins (herein, referred to as "cyclin D"), it has not been established whether HIV-1 gene products trigger either cyclin D-dependent or cyclin D-independent proliferation in non-lymphoid tissues [ 15 ] . In infected renal epithelium, HIV-1 could disrupt the inhibitory binding of pRb to E2F independent of endogenous cyclin D, analogous to transforming viral mechanisms that bypass and down-regulate endogenous cyclin D, such as SV-40 T antigen binding to pRb [ 16 ] , HHV-8 v -cyclin binding to and activating cyclin-dependent kinase-6 (CDK) [ 17 ] , and activation of cyclin E by EBV-induced c -myc [ 18 ] . Alternatively, HIV-1 could activate cyclin D-dependent proliferation, as exemplified by RSV v -src-mediated signaling [ 19 ] . In most tissues, the selective activation of these cell-cycle pathways is readily discernable.
By waiting until flies are young adults to activate gene overexpression, effects can be identified that are specific to adult aging.
In this regard, it is known that the hormonal action of estrogens may be mediated by the differential expression of estrogen receptors alpha vs betta in brain structures that activate or inhibit cell death mechanisms [ 56 ] . Although, this parameter was not directly investigated in this study, the differing influence that dietary phytoestrogens had on CALB (significant decrease) and COX-2 (significant increase) in the male frontal cortex, suggests that phytoestrogens may activate programmed cell death.
Finally, activation of MAPKs has been shown to activate the singly spliced and unspliced (genomic) latent HIV-1 virus.
In the present study we provide evidence that TNFα and a by-product of TNFα signaling, ceramide, both have the capacity to activate members of the MAPK family.
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