Words similar to activate
Example sentences for: activate
How can you use “activate” in a sentence? Here are some example sentences to help you improve your vocabulary:
While these upstream kinases lead to tyrosine phosphorylation of the adaptor and activation of downstream effectors, they usually also activate other signaling pathways that can confound analysis of the specific role of the tyrosine phosphorylated adaptor protein.
Recent evidence from gene-targeted mice suggests that Rlk may synergize with Itk in signaling from the T cell receptor to activate phospholipase C-γ [ 20].
Although it is possible that IL-10 produced by these cells inhibited T-cell activation in the synovium, TRANCE expressed by these same cells might function to activate dendritic cells and indirectly stimulate T cells, mediating inflammation in the synovium.
We have previously determined, using dose-dependent studies, that this concentration is optimal for functions of this chemokine on these embryonic fibroblasts and in processes of granulation tissue formation [ 3 4 ] ). Although chemokine concentrations of 10 -2-10 ng/ml can chemoattract and activate leukocytes, chemokines acting on other cell types such as endothelial cells, smooth muscle cells and fibroblasts require concentrations in the range of 10 2ng/ml and higher [ 4 26 27 28 ] . This is within physiological range; for example wound fluid from burn patients contain MGSA (a chemokine that is highly homologous to cCAF) concentrations of 10 2-10 3ng/ml [ 29 ] . Because both the N-terminal and C-terminal peptides of cCAF have been shown to be functional in culture and in vivo (1-4, 30), we also tested these two peptides (Fig.
Indeed, as P-TEFb is a coactivator of potent activators that mediate effects of enhancers and can itself activate transcription when placed on sites distal to promoter elements [15], it might mediate many more signaling events than those of heat shock, ultraviolet light, stress, and hypertrophy.
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