Words similar to activating
Example sentences for: activating
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Transformants were then pooled and transferred onto plates lacking histidine and leucine in order to select for peptide sequences capable of activating the lexA-operator-driven LEU2 reporter.
Further analysis revealed that a 521 base pair region of P. stutzeri ORF-F shares 80% homology with M. tuberculosis moe Z [ 17 ] . The products of the pdt locus probably function by activating, then sulfurating, a carboxylic acid precursor.
In a second group of experiments, we observed that CLENDO cells were resistant to apoptosis when treated for 72 h with sFasL or the human Fas activating antibody CH-11.
In comparison to the two general alternative mechanisms utilized by known transforming viruses to promote cell-cycle progression, namely, by activating or bypassing endogenous D-type cyclins (herein, referred to as "cyclin D"), it has not been established whether HIV-1 gene products trigger either cyclin D-dependent or cyclin D-independent proliferation in non-lymphoid tissues [ 15 ] . In infected renal epithelium, HIV-1 could disrupt the inhibitory binding of pRb to E2F independent of endogenous cyclin D, analogous to transforming viral mechanisms that bypass and down-regulate endogenous cyclin D, such as SV-40 T antigen binding to pRb [ 16 ] , HHV-8 v -cyclin binding to and activating cyclin-dependent kinase-6 (CDK) [ 17 ] , and activation of cyclin E by EBV-induced c -myc [ 18 ] . Alternatively, HIV-1 could activate cyclin D-dependent proliferation, as exemplified by RSV v -src-mediated signaling [ 19 ] . In most tissues, the selective activation of these cell-cycle pathways is readily discernable.
Unlike TNFα, other cytokines (IFNγ or sFasL) or Fas activating antibodies had little effect on the endothelial cell viability.
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