Words similar to activating
Example sentences for: activating
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In addition, short activating sequences may prove useful in the context of isolating peptides that interact with other proteins.
In comparison to the two general alternative mechanisms utilized by known transforming viruses to promote cell-cycle progression, namely, by activating or bypassing endogenous D-type cyclins (herein, referred to as "cyclin D"), it has not been established whether HIV-1 gene products trigger either cyclin D-dependent or cyclin D-independent proliferation in non-lymphoid tissues [ 15 ] . In infected renal epithelium, HIV-1 could disrupt the inhibitory binding of pRb to E2F independent of endogenous cyclin D, analogous to transforming viral mechanisms that bypass and down-regulate endogenous cyclin D, such as SV-40 T antigen binding to pRb [ 16 ] , HHV-8 v -cyclin binding to and activating cyclin-dependent kinase-6 (CDK) [ 17 ] , and activation of cyclin E by EBV-induced c -myc [ 18 ] . Alternatively, HIV-1 could activate cyclin D-dependent proliferation, as exemplified by RSV v -src-mediated signaling [ 19 ] . In most tissues, the selective activation of these cell-cycle pathways is readily discernable.
IL-1β is a proinflammataory cytokine that has myriad effects on cells, increasing proliferation, activating inflammatory responses, and inducing matrix remodeling through the production of neutral proteases.
Although Fas activating antibody, Jo2, induces apoptosis in ovarian surface epithelial cells [ 23 ] , Jo2 had no effect on CLENDO cell survival.
This association could be directed by an imperfect immunoreceptor tyrosine-based activating motif (ITAM) [ 19] or by a motif similar to immunoreceptor tyrosine-based inhibitory motif (ITIM) located in the CD5 cytoplasmic domain [ 20].
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