Words similar to activation-induced

Example sentences for: activation-induced

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Although adenoviral transduction did not induce detectable activation of resting, naïve CD4 +T cells (Figure 2), we wished to further determine whether transduction altered the activation-induced functions of this population.
In addition, IL-2 may have a role in activation-induced T-cell death, therefore causing peripheral tolerance [ 6, 7].
It is well known that apoptosis in T lymphocytes is an elaborately orchestrated process following lymphocyte activation that allows clonal expansion of the activated T cells while eventually eliminating the clone through the process of activation-induced cell death [ 30].
In induced models of autoimmunity, the CD28-B7 interaction has been shown to regulate disease susceptibility by rendering autoreactive T cells anergic, or alternatively by upregulating the threshold for autoreactive T-cell activation [ 30 ] . Furthermore, we previously showed that impaired Fas-mediated activation-induced cell death (AICD) of autoreactive T-helper-1 cells may be responsible for the development of PGIA [ 20 ] . Therefore, AICD and/or T-cell anergy, but not the CD4 +CD25 +regulatory T cells, may be responsible for deletion or inactivation of autoreactive T cells in autoimmune arthritis.
APOBEC1, for example, is involved in the C→U editing of apolipoprotein B mRNA (therein christening the family), while another family member, the activation-induced deaminase, has a vital role in adaptive immunity in that it assists in the diversification of antibodies.