Example sentences for: activation-induced

How can you use “activation-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • First, CD4 +T cells selectively proliferate in response to proteoglycan antigens [ 14 ] . Second, prevention of arthritis can be achieved by in vivo treatment with anti-CD4 monoclonal antibodies [ 15 ] . Third, arthritis can be transferred to naïve BALB/c or severe combined immunodeficient (SCID) mice using T and B cells from arthritic animals [ 16 17 18 ] . Fourth, a proteoglycan-specific T-cell hybridoma (T-helper-1 type) can induce arthritis in BALB/c mice [ 19 ] . Finally, CD4 +T cells from arthritic animals are resistant to activation-induced cell death [ 20 ] . These data suggest a breakdown of peripheral tolerance and accumulation of autoreactive T cells in the periphery.

  • In addition, IL-2 may have a role in activation-induced T-cell death, therefore causing peripheral tolerance [ 6, 7].

  • The receptor activation-induced decrease of SNIP1 is partially sensitive to the proteasome-specific inhibitor lactacystin, suggesting the involvement of proteasomal degradation (Fig.

  • Cytokines (IL-2 and IL-7) induce the expression of KLF2 in activated T cells which correlates with their survival [ 20 ] . They suggest that KLF2 may be involved in avoiding activation-induced cell death.

  • IL-2 may directly eliminate mononuclear cells through activation-induced death [ 6, 7].


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