Words similar to activation-induced
Example sentences for: activation-induced
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First, CD4 +T cells selectively proliferate in response to proteoglycan antigens [ 14 ] . Second, prevention of arthritis can be achieved by in vivo treatment with anti-CD4 monoclonal antibodies [ 15 ] . Third, arthritis can be transferred to naïve BALB/c or severe combined immunodeficient (SCID) mice using T and B cells from arthritic animals [ 16 17 18 ] . Fourth, a proteoglycan-specific T-cell hybridoma (T-helper-1 type) can induce arthritis in BALB/c mice [ 19 ] . Finally, CD4 +T cells from arthritic animals are resistant to activation-induced cell death [ 20 ] . These data suggest a breakdown of peripheral tolerance and accumulation of autoreactive T cells in the periphery.
The receptor activation-induced decrease of SNIP1 is partially sensitive to the proteasome-specific inhibitor lactacystin, suggesting the involvement of proteasomal degradation (Fig.
Further, the activation-induced expression of GFP by cells transduced with the Ad5.CMV5 vector yielded significantly better expression levels than those induced by the Ad5.UbP vector.
APOBEC1, for example, is involved in the C→U editing of apolipoprotein B mRNA (therein christening the family), while another family member, the activation-induced deaminase, has a vital role in adaptive immunity in that it assists in the diversification of antibodies.
IL-2 may directly eliminate mononuclear cells through activation-induced death [ 6, 7].
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