Example sentences for: activation

How can you use “activation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In normal PBMC only trace amounts of both genes were identified, but after activation by PHA and IL2 only granzyme B was up-regulated.

  • A description of the plasmids encoding the two components of an ecdysone inducible transcription activation system was reported previously [ 14 ] . The plasmids pGAL4-EcR and pVP16-mRXR encode proteins which heterodimerize and regulate transcription upon the addition of ecdysone type ligands (Figure 1A).

  • Thus there is interest in using this class of inhibitors for chemotherapeutic treatment of cancer and several phase I trials have been carried out [ 22 ] . Treatment of mammalian cells with rapamycin leads to dephosphorylation and activation of 4EBP, which in turn binds to and inhibits eIF4E.

  • Smad1 is translocated from the cytoplasm to the nucleus upon its activation by the BMP type I receptors [ 40 ] . The physical interaction between Smad1, Az and HsN3 suggests that BMP signaling might regulate the intracellular localization of Az and HsN3.

  • There are two possible explanations for the PKC-independent activation of K ATP by phorbol esters: 1) phorbol esters may increase K ATP activity in an intracellular ATP-independent manner and 2) phorbol esters may reduce sensitivity of K ATP to ATP.


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