Example sentences for: activation

How can you use “activation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The present study was designed as one of the steps in defining the detailed pharmacology of a set of non-selective opioid ligands and aimed at defining the activation profiles of these ligands at a well-defined system expressing only δ opioid receptors.

  • In contrast, TGF-β1 protects L929 cells from TNF cytotoxicity by upregulating the expression of antiapoptotic TIAF1, TIF2 and a novel matrix protein [ 11 12 13 14 ] . TGF-β1 blocks PH-20-increased TNF susceptibility [ 15 ] . Likewise, PH-20 inhibits TGF-β1-induced TNF-resistance [ 15 ] . TGF-β1 suppresses PH-20-mediated ERK activation [ 16 ] ; however, the ERK activation is not related with PH-20-increased TNF susceptibility in L929 cells [ 15 ] . Whether the proapoptotic p53 and WOX1 block the function of antiapoptotic TIAF1 and TIF2 is not known.

  • The activation of CaMKII then catalyzes the phosphorylation of AMPA-receptors and enhances AMPA receptor responsiveness [ 37, 39, 40, 60].

  • Associated with the increased expression was cleavage of procaspase-8 to produce the active enzyme and cleavage of Bid, indicating activation of the Fas/FasL apoptotic pathway in the course of progressive renal failure.

  • Activation of the oxidase generates intralysosomal O 2 •-that is membrane impermeable, with a short life span and is converted to H 2 O 2 instantly by the consumption of protons (see (1)).


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