Example sentences for: activators

How can you use “activators” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These hybrid molecules activate transcription [ 9 31 ] . It may be possible to produce small-molecule activators (or repressors) that bind DNA specifically, but also activate transcription of adjacent genes through a non-peptidic, more drug-like moiety.

  • When using potential activators (e.g.

  • The CXC chemokines such as IL-8 were originally identified as potent activators and chemoattractants for neutrophils, whereas the CC chemokines such as MCP-1 and RANTES mostly attract monocytes and eosinophils respectively [ 10 ] . Chemokines are secreted in a stimulus-and cell type-specific manner [ 11 12 13 14 15 16 17 ] and are regulated primarily at the level of gene transcription [ 18 19 20 21 22 23 24 ] . The transcriptional promoters of IL-8, RANTES and MCP-1 contain binding sites for the redox-responsive transcription factor NF-κB, which has been shown to be important for their regulation by viral infections and cytokines [ 18 20 23 25 26 27 28 29 30 31 32 33 34 ] .

  • Retests of individual clones revealed that ~90% were bona fide activators.

  • The plasminogen activators, tissue type and urokinase type, have been reported to be both deleterious in inflammation, owing to the proteolysis of tissue proteins, and beneficial because of fibrinolytic activity [ 26 ] . The presence of both increased urokinase and plasmin inhibitors in rheumatoid arthritis synovial tissue suggests a complex role for urokinase in this disease [ 27 28 29 ] that seems pertinent to our finding of urokinase-generated mactinin in the arthritis fluid samples.

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