Words similar to activators
Example sentences for: activators
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Sp1 and CREB interact with distinct glutamine-rich domains of TAF II 135 and TAF II 135 acts as a coactivator in vitro for these activators.
The plasminogen activators, tissue type and urokinase type, have been reported to be both deleterious in inflammation, owing to the proteolysis of tissue proteins, and beneficial because of fibrinolytic activity [ 26 ] . The presence of both increased urokinase and plasmin inhibitors in rheumatoid arthritis synovial tissue suggests a complex role for urokinase in this disease [ 27 28 29 ] that seems pertinent to our finding of urokinase-generated mactinin in the arthritis fluid samples.
LM-PCR has been used in several studies, including a systematic genome-wide location analysis of yeast transcriptional activators [ 10 ] , and an unbiased search for E2F binding sites in a subset of human promoters [ 11 ] . Studies employing the R-PCR approach include genome-wide analyses of silencing enzymes [ 12 ] and histone modifications [ 6 7 ] in yeast, and a mapping of GATA-1 binding sites within the human β-globin locus [ 13 ] .
Signaling proceeds through the Janus kinase/signal transducers and activators of transcription (JAK/STAT) or the ras-mitogen-activated protein (MAP) kinase pathways [for a review see [ 7 ] ].
However, structural features such as acidity observed in previous studies were not absolute requirements for activation [ 11 20 21 ] . Charge neutral and basic peptide activators arose at significant frequencies.