Example sentences for: pcu

How can you use “pcu” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The eight CSN subunits show a one-to-one relationship to components of the 19S proteasome lid complex [ 17, 18, 19] and, like pcu3 and pcu4 , at least seven of the eight human subunits are conserved in fission yeast, but not in budding yeast.

  • Pcu3-Myc immunoprecipitated from lysates of cells expressing HA-tagged Csn1p together with Pcu3p-Myc from the endogenous promoters revealed co-precipitation of Csn1p-HA.

  • This localization pattern was fully preserved in all four csn mutants, indicating that CSN does not regulate the subcellular localization of Pcu3p.

  • Size exclusion chromatography of lysates prepared from cells harboring epitope-tagged Pcu3p or CSN subunits at the endogenous genomic loci, revealed precise co-elution of Pcu3p with CSN subunits 1, 3, 4, and 5 in high molecular weight fractions corresponding to approximately 550 kDa (Fig.

  • Mutation of CSN increases Pcu3p-dependent polyubiquitylation activity


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