Example sentences for: pcu

How can you use “pcu” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Second, replacing lysine 729, which is homologous to the conserved neddylation sites in other cullins, with arginine, completely abolished the slower migrating, modified form of Pcu3p (Fig.

  • Pcu3p interacts with CSN

  • recently provided evidence for a cullin deneddylating activity of CSN by demonstrating that a partially purified preparation of the pig CSN can deneddylate the fission yeast cullin Pcu1p in vitro [ 10].

  • In such a scenario, no enzymatic activity of purified CSN toward neddylated Pcu3p would be expected in vitro .

  • We have examined this question by determining the effect of disruption of several CSN subunits on Pcu3p neddylation, localization, and ubiquitin ligase activity.


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