Words similar to pd

Example sentences for: pd

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T1DM susceptibility in the NOD mouse is linked to I-A g7, the murine MHC class II gene that encodes a histidine at position 56 and a serine at position 57 in the β chain, in place of the more frequent proline 56β and aspartic acid 57β [ 3 ] . The development of diabetes is prevented in NOD.PD mice (which are NOD mice with I-A g7) that carry a β chain transgene with site-specific mutations that restore proline and aspartic acid at positions 56β and 57β, respectively [ 4 ] . Furthermore, because of the two amino acid changes in the additional (transgenic) MHC class II allele β chain in NOD.PD mice, NOD.PD mice recognize three additional peptide epitopes in the glutamic acid decarboxylase 65 (GAD65) autoantigen [ 5 ] .
Our results suggest that routine P&PD is unnecessary.
The CSC-induced increase in IL-1β expression was also reduced by treatment of the cells with PD98059 or the NFκB inhibitor, PDTC (Fig.
AG126 and PD98059 were purchased from Calbiochem (San Diego, CA).
1A) versus an ~40% inhibition observed after the 16-hour incubation used in the experiments with rapamycin and PD98059 (Fig.