Example sentences for: pca

How can you use “pca” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • PCA, Spearman's rank correlations, quadratic regression classification and cross-validation were programmed in MatLab release 12.

  • Subsequent cycles of clustering were initialized similarly, except that PCA was performed on the respective data subset used in that clustering cycle.

  • PCA is a statistical technique to reduce the dimensionality of a dataset while retaining as much of the variability as possible [ 15 ] . Each principal component captures as much variability as possible with a linear combination of the data and is uncorrelated with all other principal components.

  • We were curious to know whether the expression changes observed in LNCaP would also occur in other androgen-responsive human prostate cancer cell lines (MDA PCa 2a, MDA PCa 2b, and LAPC-4), or in LNCaP and LAPC-4 subclones carried in androgen-depleted conditions for extended periods.

  • An association between autocrine IL-6 and PCA has been known for some time [ 16 17 ] . The change in prostate cell phenotype from paracrine IL-6-stimulated to autocrine IL-6-stimulated is believed to be a contributing factor in the progression from benign hyperplasia to neoplasia [ 17 ] . IL-6 is also implicated in the development of cancer cell resistance to chemotherapy in PCA patients [ 18 19 ] . In other studies, a chimeric protein consisting of an anti-IL-6 Ab fused to Pseudomonas exotoxin was found to inhibit proliferation of prostate carcinoma cell lines [ 20 ] . Exogenous IL-6 activated androgen responsive gene expression in the absence of androgens in human LNCaP cells [ 21 ] . More work is needed to clarify the role of IL-6 in prostate neoplasia.


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