Words similar to proteoglycans
Example sentences for: proteoglycans
How can you use “proteoglycans” in a sentence? Here are some example sentences to help you improve your vocabulary:
Alcian Blue (Sigma) was used to detect extracellular matrix proteoglycans in chondrogenic cultures.
Cell-associated HS proteoglycans can undergo regulated shedding from the membrane into the soluble extracellular matrix or culturing medium converting the membrane anchored molecules into soluble effectors [ 1 2 ] . In the conditioned media of all the tested batches of retinoblastoma cells, we detected heparin and HS with binding affinity for PEDF.
To identify the cell surface proteoglycans that may serve as receptors for III1-C, RASMCs were labeled with 35SO 4 and cell lysates were applied to III1-C and III 11-C columns.
Other workers and ourselves have previously examined the effects of TGF-β1 gene transfer on matrix synthesis in chondrocyte cultures, demonstrating a significant stimulation in the production of proteoglycans [ 9 ] . In addition, we have demonstrated that the TGF-β1 gene was able to overcome the inhibitory effects of IL-1β on matrix metabolism in chondrocytes in culture [ 20 ] .
Deletion of the 13q region is associated with human 13q syndrome, a developmental disorder [ 24 ] . Some of the proteoglycans play important functional roles in neurogenesis, axon guidance, synapse development [ 25 ] , and cellular growth and differentiation [ 26 27 23 ] . Mutations in GPC3 cause Simpson-Golabi-Behmel syndrome [ 28 29 ] , however, no mutations were detected in the GPC5 and GPC6 genes [ 30 ] . The glypican1 gene has been suggested to be a good candidate for brachydactyly type E [ 31 ] . Given that, GPC5 is highly expressed in brain and mutations in other genes of the glypican families are associated with developmental disorder; GPC5 could be a potential candidate gene for Bipolar disorder.
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