Example sentences for: proteoglycans

How can you use “proteoglycans” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • After 28 d in culture, more than 50% of all cells exhibited robust staining for Alcian Blue, a marker specific for extracellular matrix proteoglycans.

  • At the epithelium, GnRH neurons cross the basal laminae to initiate their migratory phase [ 15 ] . The olfactory nerve expresses several matrix molecules [heparan and keratan sulfate proteoglycans [ 26 ] , laminin [ 27 ] , phosphocan [ 28 ] , lectin-binding domains [ 29 ] ]. Any or all of these may serve as substrates for proteolysis.

  • Proteoglycan-induced arthritis (PGIA) is a novel autoimmune murine model that is induced by systemic immunization of BALB/c mice with cartilage proteoglycans [ 12 13 ] . The development of PGIA is based on the cross-reactive immune response between immunizing human and mouse (self) cartilage proteoglycans in genetically susceptible BALB/c mice [ 12 13 ] . Several lines of evidence indicate T-cell involvement in the pathogenesis of PGIA.

  • This result is consistent with the idea that HSPGs but not chondroitin sulfate proteoglycans serve as signaling receptors for III1-C.

  • Cell-associated HS proteoglycans can undergo regulated shedding from the membrane into the soluble extracellular matrix or culturing medium converting the membrane anchored molecules into soluble effectors [ 1 2 ] . In the conditioned media of all the tested batches of retinoblastoma cells, we detected heparin and HS with binding affinity for PEDF.


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