Words similar to proteoglycans
Example sentences for: proteoglycans
How can you use “proteoglycans” in a sentence? Here are some example sentences to help you improve your vocabulary:
Moreover, Frizzled receptors, Versican and other proteoglycans which contribute to Wnt protein activity are also controlled by Wnt signaling, as previously described in Drosophila [ 28 29 ] . At the level of transcriptional regulation, we found up-regulation of CBP/P300, which partners with β-catenin [ 30 31 ] but also TLE/Groucho, which is an inhibitor of TCF function [ 32 ] . These responses suggest a rich system of homeostasis and feedback control mechanisms, but they complicate the interpretation of experimental studies of Wnt signal transduction in which the time course of induction cannot be controlled easily.
Cell-associated HS proteoglycans can undergo regulated shedding from the membrane into the soluble extracellular matrix or culturing medium converting the membrane anchored molecules into soluble effectors [ 1 2 ] . In the conditioned media of all the tested batches of retinoblastoma cells, we detected heparin and HS with binding affinity for PEDF.
Proteoglycan-induced arthritis (PGIA) is a novel autoimmune murine model that is induced by systemic immunization of BALB/c mice with cartilage proteoglycans [ 12 13 ] . The development of PGIA is based on the cross-reactive immune response between immunizing human and mouse (self) cartilage proteoglycans in genetically susceptible BALB/c mice [ 12 13 ] . Several lines of evidence indicate T-cell involvement in the pathogenesis of PGIA.
Additional investigations identified myelin-associated molecules, including Nogo (formerly NI-35/250), myelin-associated glycoprotein (MAG), and chondroitin sulfate proteoglycans, that inhibit neurite growth [ 10, 11, 12, 13, 14, 15, 16, 17, 18, 19].
We find that cells can adhere and spread on III1-C and that two classes of receptors function in cell adhesion to III1-C; integrins and cell-surface proteoglycans.
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