Example sentences for: proteoglycans

How can you use “proteoglycans” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Both cell adhesion and connective tissue remodeling are indispensable for normal development and maintenance of tissue integrity [ 13 14 15 ] . The differential expression of proteoglycans, collagens and cell adhesion molecules (for example cadherin 13) might be involved in genital morphogenesis and later stability of sexually dimorphic traits of the external genitalia.

  • After 28 d in culture, more than 50% of all cells exhibited robust staining for Alcian Blue, a marker specific for extracellular matrix proteoglycans.

  • Aggrecan and versican are aggregating proteoglycans that are key constituents found in the extracellular matrix [ 41 ] . Both proteoglycans contain amino-terminal hyaluronic acid-binding regions, central core glycosaminoglycan attachment domains, and carboxyl-terminal domains containing EGF-like modules (one in aggrecan and two in versican), C-type lectin like modules and complement regulatory protein-like modules [ 49 50 ] . Fibulin-1 exhibits calcium-dependent binding to the carboxyl-terminal domain of aggrecan and versican [ 41 ] . The binding site of aggrecan to fibulin-1 maps to the type II EGF-like modules 8-9 and the carboxyl-terminal domain of fibulin-1 [ 41 ] . The binding site of versican to fibulin-1 maps to the type II EGF-like modules 2-8 of fibulin-1 [ 41 ] .

  • Cell-associated HS proteoglycans can undergo regulated shedding from the membrane into the soluble extracellular matrix or culturing medium converting the membrane anchored molecules into soluble effectors [ 1 2 ] . In the conditioned media of all the tested batches of retinoblastoma cells, we detected heparin and HS with binding affinity for PEDF.

  • To identify the cell surface proteoglycans that may serve as receptors for III1-C, RASMCs were labeled with 35SO 4 and cell lysates were applied to III1-C and III 11-C columns.


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