Example sentences for: proteoglycans

How can you use “proteoglycans” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Alcian Blue (Sigma) was used to detect extracellular matrix proteoglycans in chondrogenic cultures.

  • Additional investigations identified myelin-associated molecules, including Nogo (formerly NI-35/250), myelin-associated glycoprotein (MAG), and chondroitin sulfate proteoglycans, that inhibit neurite growth [ 10, 11, 12, 13, 14, 15, 16, 17, 18, 19].

  • Deletion of the 13q region is associated with human 13q syndrome, a developmental disorder [ 24 ] . Some of the proteoglycans play important functional roles in neurogenesis, axon guidance, synapse development [ 25 ] , and cellular growth and differentiation [ 26 27 23 ] . Mutations in GPC3 cause Simpson-Golabi-Behmel syndrome [ 28 29 ] , however, no mutations were detected in the GPC5 and GPC6 genes [ 30 ] . The glypican1 gene has been suggested to be a good candidate for brachydactyly type E [ 31 ] . Given that, GPC5 is highly expressed in brain and mutations in other genes of the glypican families are associated with developmental disorder; GPC5 could be a potential candidate gene for Bipolar disorder.

  • The retina and malignant solid tumors also produce the sulfated GAGs [ 1 2 22 23 24 25 26 ] . Although HSs are mostly found as proteoglycans associated with the basal lamina or the plasma membrane, the presence of HSs in the culturing medium might be a result of shedding or release of their extracellular domains from the cell membranes as soluble components.

  • Maxisorp immunoplates (Nunc, Rochester, NY, USA) were coated with human or mouse cartilage proteoglycans (0.


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