Example sentences for: proteolytic

How can you use “proteolytic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This small latent complex may be secreted inefficiently from the cell surface at relatively slow rates [ 23 ] . However, when the small latent complex is bound by the latent transforming growth factor β-binding protein via a disulfide bond to the latency-associated peptide, the result is the formation of a large latent complex which may be secreted efficiently and at a relatively high rate compared to the small latent complex [ 23 ] . Latent TGF-β is then released from the extracellular matrix via proteolytic cleavage from the large latent complex, and the resulting active TGF-β is now able to bind to the appropriate TGF-β cell-surface receptors [ 24 ] .

  • The sequence of proteolytic events, by which NE leads to collagen degradation, is incompletely defined.

  • 3. In addition, we found that certain cysteine substitutions in EGF-like domains and located immediately N-terminal of LTBP-like domains, cause protein instability and greatly reduced matrix deposition [ 9 ] . Taken together, our data support a model in which misfolding or partial deletion of LTBP-like domains results in proteolytic cleavage of the mutant fibrillin molecules.

  • Proteolytic cleavage of the latent forms can result in generation of active proteases [ 24, 25].

  • We have shown here that IP-10 and MIG, two chemokines that are secreted from lung lymphocytes of participants with emphysema, upregulate specifically MMP12 and thus favor a proteolytic microenvironment that facilitates lung destruction.


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