Words similar to proteolysis

Example sentences for: proteolysis

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Removal of the TPR domain of PP5 by limited proteolysis increases enzyme activity and the TPR domain binds lipid [ 7 8 9 19 20 ] . Using conditions similar to those employed with PP5, digestion of Ppt1p with trypsin in the absence of lipid produced a 44 kDa catalytic fragment that was stable for at least 30 min and a 20 kDa fragment that was degraded within 30 min (Fig.
p27 specifically inhibits CDKs, which mediate entry into S phase [ 10 11 ] . The level of p27 is higher in quiescent than in proliferating cells, and this increase in p27 abundance is required for an effective cell cycle exit [ 12 ] . The cell cycle-dependent variations in p27 levels are not reflected by similar changes in p27 mRNA [ 13 ] . Many aggressive prostate cancers display decreased p27 protein levels in the presence of high p27 mRNA [ 14 ] , suggesting that p27 depletion may result from ectopic proteolysis.
5 mM DTT was included to inactivate any residual PMSF, and then 2 mM CaCl 2 was added to allow proteolysis of Boi1-PH.
Nearly half of the genes (45) in this category (92) are involved in proteolysis (see Additional data files).
Using reaction conditions that were otherwise the same as those used when PS was the bulk lipid, no proteolysis of Boi1-PH was detected in the presence of any of the phosphatidylinositides except PIP 2 , which stimulated only a small amount of proteolysis (Fig.