Example sentences for: proteolysis

How can you use “proteolysis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • p27 specifically inhibits CDKs, which mediate entry into S phase [ 10 11 ] . The level of p27 is higher in quiescent than in proliferating cells, and this increase in p27 abundance is required for an effective cell cycle exit [ 12 ] . The cell cycle-dependent variations in p27 levels are not reflected by similar changes in p27 mRNA [ 13 ] . Many aggressive prostate cancers display decreased p27 protein levels in the presence of high p27 mRNA [ 14 ] , suggesting that p27 depletion may result from ectopic proteolysis.

  • While F-box deleted Pop2p expressed from plasmids reduced Rum1p half-life to ~20 minutes in pop2 mutants, F-box-deleted Pop1p was completely defective in rescuing the Rum1p proteolysis defect of pop1 mutants (Fig.

  • These fragments, which are derived from the TPR domain, were not observed in the absence of AA, suggesting that lipid binding alters the conformation of this domain and its susceptibility to proteolysis.

  • Each of the proteolysis experiments was performed at least three times, with similar results.

  • In contrast, TBP and TAF II 135 are readily detected in extracts made from differentiated cells treated with MG132, ALLN, and the proteasome-specific inhibitor lactacystin (our unpublished data) showing that their disappearance is due to selective proteolysis.


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