Example sentences for: proteoglycan

How can you use “proteoglycan” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a control, the same number of CD4 +CD25 -T cells, together with arthritogenic spleen cells that were depleted of CD25 +cells, and proteoglycan, were also adoptively transferred into SCID mice.

  • a total of 1 × 10 7CD25 +and CD25 -spleen cells, together with 100 μg proteoglycan, were injected intraperitoneally into SCID mice.

  • However, CD28-deficient T cells from proteoglycan-immunized animals can proliferate in response to proteoglycan stimulation in vitro , albeit at a rate lower than that in wild-type T cells, which is consistent with the report by Oliveira-dos-Santos et al . [ 30 ] . It has been demonstrated that, in the absence of CD28 engagement, T cells require very high TCR occupancy and prolonged stimulation, whereas CD28 costimulation allows T cells to respond to lower degrees of TCR occupancy [ 30 31 ] . In support of this observation, CD28 -/-mice can still mount immune responses, which vary in magnitude and efficiency depending on the antigen or infectious agent [ 30 32 ] . Our results and those reported by others [ 30 ] suggest that CD28 may regulate the threshold for T-cell activation.

  • Heparitinase and chondroitinase ABC treatment of the 35SO 4 labeled samples revealed that the 450 kDa proteoglycan was composed mostly of HSPGs (Fig.

  • This proteoglycan resisted elution by 8 M urea but was eluted by boiling the Sepharose beads in SDS (Fig.


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