Example sentences for: proteoglycan

How can you use “proteoglycan” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In identifying targets for therapeutic intervention, it is important to note that the loss of collagen, rather than proteoglycan, is correlated with disease severity [ 6 ] . Furthermore, whereas lost proteoglycan is replaced rapidly, degraded collagen is resynthesized very slowly [ 7 8 ] . Consequently, understanding collagen degradation and providing therapeutics to prevent it are valuable aims.

  • Heparitinase and chondroitinase ABC treatment of the 35SO 4 labeled samples revealed that the 450 kDa proteoglycan was composed mostly of HSPGs (Fig.

  • 5 × 10 4) with 1 μg/ml soluble anti-CD3 for 3 days or 50 μg/ml proteoglycan for 5 days, and T-cell proliferation was determined by [ 3H]thymidine incorporation.

  • Laminin is a glycoprotein composed of three chains, A, B1, and B2 in a cross-shaped molecule; this protein is found in basement membranes where it interacts with other such components as collagen IV, heparan-sulfate proteoglycan, and nidogen [ 45 ] . Laminin contains EGF-like modules in the amino-terminal region of the A, B1, and B2 chains [ 45 ] . Surprisingly, these modules do not appear to be involved in the binding of fibulin-1.

  • Magnetic resonance imaging techniques are actively being developed to image the collagen component of tissue, which can be incorporated into future studies [ 25 ] . Human osteoarthritic tissue is, by histologic measures, spatially heterogeneous in both collagen damage and degree of proteoglycan depletion.


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