Words similar to proteoglycan
Example sentences for: proteoglycan
How can you use “proteoglycan” in a sentence? Here are some example sentences to help you improve your vocabulary:
Articular cartilage fragments shaved from the femoral condyles were placed into 1 ml Neuman-Tyell serum-free medium (Gibco, New York, USA) to measure the rate of proteoglycan synthesis.
Typically, in the primary form of PGIA, BALB/c mice developed swelling and redness in one or more limbs 7-14 days after the third injection with proteoglycan and adjuvant.
Chondroitin sulfate proteoglycan (CSPG) staining was carried out in adjacent spinal cord sections using the monoclonal antibody CS-56 raised against chicken chondroitin sulfate.
For instance, IL-1-degraded cartilage tissues and cell suspensions are frequently employed as model systems to study cartilage metabolism under osteoarthritis-like conditions [ 1 2 3 4 ] and to assess the efficacy of various drug therapies [ 5 6 7 8 9 ] . IL-1 signals cells via cell surface receptors to upregulate proteases, matrix metalloproteinases and aggrecanase, while downregulating matrix metalloproteinase inhibition and proteoglycan synthesis [ 10 11 ] . The ultimate effect of these metabolic changes include damage to the ECM, loss of ECM components (especially proteoglycan), and alteration of the normal balance of catabolic and anabolic processes that regulate cartilage ECM composition.
Purified CD4 +CD25 +regulatory T cells (3-20 × 10 5) from naïve BALB/c mice, together with 10 7spleen cells from arthritic mice that were depleted of CD25 +T cells and 100 μg proteoglycan, were injected intraperitoneally into SCID mice [ 18 ] , and the incidence and severity of disease were monitored.
Loading...