Example sentences for: proteoglycan

How can you use “proteoglycan” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • High-density cartilage proteoglycan (aggrecan) was purified from human cartilage, by CsCl gradient centrifugation, and depleted of glycosaminoglycan side chains as described previously [ 21 ] . Female BALB/c mice (National Cancer Institute, Friedrich, MD, USA, or The Jackson Laboratory, Bar Harbor, ME, USA) and CD28-deficient mice (The Jackson Laboratory) were immunized intraperitoneally with cartilage proteoglycan (100 μg protein) in complete Freund's adjuvant on day 0, and boosted with proteoglycan in incomplete Freund's adjuvant on days 21 and 42.

  • Antigen-specific T-cell responses were measured in quadriplicate samples of spleen cells (3 × 10 5cells/well) cultured in the presence of 50 μg proteoglycan protein/ml.

  • In identifying targets for therapeutic intervention, it is important to note that the loss of collagen, rather than proteoglycan, is correlated with disease severity [ 6 ] . Furthermore, whereas lost proteoglycan is replaced rapidly, degraded collagen is resynthesized very slowly [ 7 8 ] . Consequently, understanding collagen degradation and providing therapeutics to prevent it are valuable aims.

  • Chondroitin sulfate proteoglycan (CSPG) staining was carried out in adjacent spinal cord sections using the monoclonal antibody CS-56 raised against chicken chondroitin sulfate.

  • 5 × 10 4) with 1 μg/ml soluble anti-CD3 for 3 days or 50 μg/ml proteoglycan for 5 days, and T-cell proliferation was determined by [ 3H]thymidine incorporation.


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