Example sentences for: proteoglycan

How can you use “proteoglycan” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine whether overexpression of TGF-β1 had effects on cartilage metabolism in naïve and AIA rabbit joints, GAG synthesis by articular cartilage and GAGs released into synovial fluid as a result of proteoglycan breakdown were measured.

  • Purified CD4 +CD25 +regulatory T cells (3-20 × 10 5) from naïve BALB/c mice, together with 10 7spleen cells from arthritic mice that were depleted of CD25 +T cells and 100 μg proteoglycan, were injected intraperitoneally into SCID mice [ 18 ] , and the incidence and severity of disease were monitored.

  • The proteoglycan content of the cartilage was notably improved.

  • Antigen-specific T-cell responses were measured in quadriplicate samples of spleen cells (3 × 10 5cells/well) cultured in the presence of 50 μg proteoglycan protein/ml.

  • 3a,3b), and the disease continued to progress in saline-treated mice at 6 weeks, with increased cell proliferation and inflammatory cell infiltration, erosion of cartilage and bone, and loss of proteoglycan from the cartilage (Fig.


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