Example sentences for: polya

How can you use “polya” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 2) corresponds to the enteric smooth muscle form of gamma actin (Accession number T60048), which according to GenBank's annotation for that accession number is a possible reversed clone because polyT (or polyA in its complementary strand) was not found within it.

  • Microarrays are tools for functional genomics research that are manufactured by depositing spots of DNA onto a glass or nylon substrate [ 1 2 ] . The spots' DNA are often obtained from many different clones in a cDNA library, each of which may contain a stretch of polyA originating from the mRNA in the pool from which the library was derived.

  • When microarrays were first being developed, investigators described situations in which their microarray hybridization data were dominated by the "polyA effect", in which poly(T)-containing molecules, which are produced by the reverse transcription of a poly(A) +RNA mixture, bind promiscuously to the poly(A) stretches of the DNA in microarray spots.

  • Three of these clones are among the outlier group for which the polyA signal is greater than 12000 phosphorimager units.

  • We were surprised to find that there appear to be prominent artifacts related to promiscuous polyA/polyT hybridization only with very strongly expressed genes , which might be due to the formation of hybridization heteropolymers at the corresponding microarray spots.


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