Example sentences for: polya

How can you use “polya” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a result, we undertook a search for the presence of the polyA effect, in which we made a spot-by-spot comparison of a microarray that was hybridized with an oligo(dT) probe, versus the same microarray hybridized using a first strand cDNA probe produced from skeletal muscle mRNA.

  • When microarrays were first being developed, investigators described situations in which their microarray hybridization data were dominated by the "polyA effect", in which poly(T)-containing molecules, which are produced by the reverse transcription of a poly(A) +RNA mixture, bind promiscuously to the poly(A) stretches of the DNA in microarray spots.

  • Despite the use of this blocking procedure, when microarray hybridization results obtained using probes derived from mRNA from two different sources are nearly the same, one cannot be certain that the similarity of the results is due to the similarity of the different mRNA sources, rather than to incomplete blockage of the polyA effect in both of the hybridizations.

  • To investigate the polyA effect as a potential artifact, we performed the following experiment, using essentially the approach described in [ 4 ] . Oligo(dT) (10-20 mer mixture, Research Genetics cat.

  • Template-independent RNA polymerases (nucleotidyltransferases) include CCA-adding enzymes, polyA polymerases, uridylyl transferases and oligoA-synthetases.


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