Words similar to phentermine
Example sentences for: phentermine
How can you use “phentermine” in a sentence? Here are some example sentences to help you improve your vocabulary:
Initial reports of remarkably high prevalence of aortic and mitral regurgitation (AR and MR) as assessed by echocardiography in five separate populations [ 2 ] were subsequently supported by most [ 3 4 5 ] but not all investigators [ 6 ] . These uncontrolled reports were soon followed by a series of studies in which prevalence of echocardiographically-defined AR and MR were assessed in persons who had taken fenfluramine, dexfenfluramine, phentermine, or combinations of these medications and compared to unexposed, matched control populations [ 7 8 9 10 11 12 13 14 15 ] . The most recent of these studies found 30% of persons currently taking fenfluramine or dexfenfluramine had mild or greater AR or moderate or greater MR, similar to the very high prevalence reported in older studies [ 15 ] . The only prospective study found a significant, exposure-related increase in the risk of clinically diagnosed valve disease among users of fenfluramine and dexfenfluramine, but not phentermine [ 16 ] .
Some recent reviews conclude that the risks associated with fenfluramine and dexfenfluramine are similar, real but modest for aortic valve disease, and barely detectable for mitral valve disease; phentermine appears not to be associated with increased risk [ 17 18 19 20 ] . Nevertheless, interpretation of the results of these studies has been so varied that some authors have even questioned any causal relationship for fenfluramine exposure [ 21 ] . However, analyses to date have not formally considered major biases that would act to deflate the actual risk associated with fenfluramine use.
Doctors reported that fenfluramine and phentermine, a popular diet pill combination, may cause severe heart-valve disease . The story is all over front pages and the TV news because the pills are prescribed about 20 million times a year.
Since the initial report by Connolly, et al [ 1 ] of valvulopathy in women taking the combination of fenfluramine and phentermine (fen-phen), controversy has surrounded the issue of associated risk.
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