Words similar to phenotypically
Example sentences for: phenotypically
How can you use “phenotypically” in a sentence? Here are some example sentences to help you improve your vocabulary:
We could not identify mutations in the AR gene in two phenotypically female individuals with complete AIS.
Individuals with inactivating mutations of their androgen receptor (AR) (androgen insensitivity syndromes (AIS)) are phenotypically female in appearance and behavior and lack male sex accessory organs (prostate, seminal vesicles and Cowper's glands) despite the presence of testes, high levels of testosterone and a Y chromosome [ 1].
As specialized proteins of the intermediate filament protein family, lamin A/C is found at the inner nuclear membrane where it forms a scaffold that interacts with a network of membrane bound and nucleoplasmic proteins in addition to chromatin [ 3 4 5 ] . Mutations in the gene encoding the nuclear membrane protein emerin produce autosomal recessive Emery Dreifuss Muscular Dystrophy, a disorder that phenotypically overlaps the neuromuscular and cardiovascular features seen with lamin A/C mutations [ 6 ] . Consistent with this, lamin A/C directly binds emerin [ 7 8 ] . Lamins A and C are broadly expressed in many different cell types and are primarily expressed in terminally differentiated cells.
In 38 of the patients, we analyzed followup PB samples that had tumor cells identified on smear and a phenotypically abnormal population identified by flow cytometry.
TBX2 showed an almost identical expression profile to TBX3 , whereas high TBX5 expression appeared to be restricted to foreskin fibroblasts from normal males (including those from the phenotypically female mosaic patient ARD364).
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