Words similar to phenotypic
Example sentences for: phenotypic
How can you use “phenotypic” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, in order to make best use of the information now available from the sequenced genome, phenotypic information is needed.
Whether mesothelin and SL-1 are direct targets of Wnt-1 and Wnt-5a, respectively, and whether alterations in their expression are responsible for the observed phenotypic changes in Wnt-5a/Rfz-2/C57mg cells, has yet to be determined.
The dsRNA, in contrast, is known to be extremely specific for its intended target, such that a single nucleotide mismatch prevents its action [ 17 ] . This has allowed us to create specific phenotypic loss of PfPP1.
Cumulatively, however, these observations do suggest a mechanism whereby HIV-1 expression in renal epithelium may induce cyclin D 1 : activation of Src-family kinases by Nef would be expected to up-regulate cyclin D 1 gene expression and promote the synthesis and stabilization of cyclin D 1 protein via Src-Ras-MAPK and Src-PI3K-mTOR signal transduction pathways, respectively [ 32 33 34 ] . Interestingly, our unpublished in vitro observations and published data showing marked expression of basic fibroblast growth factor in the interstitium of HIVAN kidneys [ 35 ] suggest that soluble mitogens may be important cofactors with HIV-1 expression to induce cyclin D 1 . Thus, interrupting HIV-1 gene expression should down-regulate cyclin D 1 and correct the phenotypic abnormalities in infected podocytes.
We found that the phenotypic difference was not so dramatic on the laterals, as at the restrictive condition approximately 55% of laterals were split or multipled while at the permissive condition about 35% were split or multipled.
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