Example sentences for: phenotype

How can you use “phenotype” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Notably, no cells contained both IFN-γ and LT-α mRNAs, cytokines that are thought to define the T-helper (Th)1 phenotype [ 9].

  • Second, mutants were identified on the basis of the phenotype of increased life span under normal conditions, as opposed to some surrogate phenotype expected to correlate with life span, such as increased stress resistance.

  • Therefore, although not proved, the CFEOM1 phenotype in these 6 families seems likely to result from mutations in the FEOM1 gene.

  • For example, early investigators observed that transfection of untransformed B cells with a plasmid for constitutive expression of IL-6 conferred the tumorigenic phenotype on the cells [ 2 ] . IL-6 is a key factor in myeloma progression and survival [ 3 4 ] , and also in Kaposi's sarcoma, a solid tumor [ 5 ] . In myeloma, the standard therapy for treatment includes prednisone, which acts by inhibiting IL-6 synthesis.

  • Combining detailed renal phenotype analysis with gene expression profiling of hyperglycemic mouse models of type 1 (streptozotocin [STZ]) and type 2 (db/db) diabetes, we recently reported that decreased mRNA levels of CD36 in kidneys were strongly correlated with albuminuria [5].


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