Example sentences for: phenotype

How can you use “phenotype” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mutations will typically not affect the phenotype of the offspring virion, which is determined by the distribution of mutant or wild-type capsid proteins in the cell.

  • Notably, no cells contained both IFN-γ and LT-α mRNAs, cytokines that are thought to define the T-helper (Th)1 phenotype [ 9].

  • First, PTEN's protein phosphatase activity is able to down-regulate focal adhesion kinase (FAK) phosphorylation, which leads to the inactivation of the Ras/MAP kinase pathway [ 19 20 21 ] . Second, its lipid phosphatase activity targets the second messenger phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P 3 ] and thereby blocks activation of the protein kinase B (PKB/Akt) pathway [ 11 18 22 23 24 ] . Whereas both of the above pathways are intimately involved in the control of cell growth and survival, PTEN-regulated FAK activity further appears to impinge on cell adhesion, cell migration, and cell invasion [ 20 21 ] . It therefore emerges that the loss of PTEN activity may confer increased survival ability, proliferative potential, and invasive capacity on cells, and thereby may promote progression towards a more malignant phenotype.

  • We did not detect any mutant phenotype in adult aristae of fz , Van Gogh ( Vang ), dishevelled ( dsh ), starry night ( stan ) also known as - Flamingo ( fmi ) or prickle ( pk ) mutants [ 1 ] . It was surprising that upstream members of the fz pathway did not show a mutant phenotype while downstream members did.

  • 1) transcripts or proteins with altered expression best discriminate CONT from SN50-treated explants with 100% sensitivity and specificity [ 69 ] . PNN analyses identify the relative importance (0-1, with 0 being of no relative importance and 1 being relatively most important) of gene and protein expression changes in defining the SN50 phenotype.


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