Words similar to phenyl
Example sentences for: phenyl
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Analysis of biophores #1, #2 (#4, #5) showed that both of them occur in substituted 5-[4-(benzyloxy) phenyl]-1,3,4-oxadiazol-2-(3H)-ones and their analogs (Figure 1), many of which are known to be strong MAO-B inhibitors [ 9 ] . Biophore #2 represents a flexible -CH 2 O- bridge between aryl moieties and was found to enhance the activity and selectivity of the inhibitors as shown in the original work [ 9 ] . Biophores #1 and #2 include aromatic moieties, whose main function is presumably to bind to the hydrophobic site of MAO.
The single crystal X-ray structure [ 14 ] and the 2-D NMR (CDCl 3 ) [ 6d ] of Taxotere likewise demonstrate hydrophobic association, in this case between the tert -butyl and the C2 phenyl group.
5, 100 mM NaCl, 1 mM EGTA, and 4 mM MgSO 4 . Cells were then resuspended in 0.6 ml of the same buffer plus 1% β-mercaptoethanol, 0.5 mM phenyl methyl sulfonyl fluoride, 50 μg/ml leupeptin, 4 μg/ml aprotinin, and 15 μl/ml of protease inhibitor cocktail P8215 (Sigma).
[ 11 12 ] Structure 1 corresponds to the non-polar conformation observed as the predominant species in CDC1 3 or CD 2 Cl 2 as depicted in Figure 3. Characteristic of the form is the "hydrophobic collapse" [ 13 ] of the benzamido phenyl at C3' and the benzoyl phenyl at C2.
1 M Tris-HCl, pH 7.4, 0.01 M EDTA and 1 mM phenyl methyl sulfonyl fluoride).