Words similar to pathology
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Example sentences for: pathology
How can you use “pathology” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the group of IFN-γR-/- mice receiving sublethal (300 Rads) whole body irradiation 2 months after infection all examined animals exhibited vascular pathology (Table 1).
To examine the effects of TGF-β1 on joint pathology, we used adenovirus-mediated intra-articular gene delivery to confer sustained intra-articular TGF-β1 expression in both naïve and arthritic rabbit knee joints.
Within the MMP family, MMP-1 (collagenase-1) and MMP-13 (collagenase-3) are expressed in arthritic joints, and efficiently degrade type II collagen [ 9 ] . MMP-13 is more effective than MMP-1 in cleaving type II collagen, but it is debated which is the principal collagenase in vivo [ 10 11 ] . These enzymes have been implicated in the pathology of rheumatoid arthritis (RA) and osteoarthritis (OA), and have long been therapeutic targets [ 12 ] . Historically, inhibition of MMP-active sites has been a strategy; however, with wide-ranging side-effects and lack of efficacy, these studies are proving unfruitful in providing an effective drug [ 13 ] .
We have previously demonstrated an excessive degree of apoptosis in patients with gastritis induced by H. pylori , and that the degree of apoptosis could be reduced by dietary supplementation with vitamin C, irrespective of whether the infection was cleared or not [ 13 ] . This observation was suggestive that dietary antioxidants could limit the gut pathology by limiting cell death mechanisms.
These dimensions have been assessed in the modern era of stroke clinical trials by clinical criteria at the bedside, usually aided by the exclusion of cerebral hemorrhage or other non-ischemic pathology by non-contrast computed tomography (CT) scan as the only imaging tool required.
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