Example sentences for: pathophysiology

How can you use “pathophysiology” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The pathophysiology of type 2 diabetes involves, in part, a “relative” deficiency of insulin.

  • Normally α-synuclein is present in the synaptic nerve terminals (including those of cholinergic neurons [ 37 38 ] ) but in AD its processing is altered, causing it to be abnormally deposited in plaques composed primarily of aggregates of β-amyloid peptide [ 39 ] . However, how this abnormal turnover of α-synuclein contributes to the pathophysiology of AD remains to be determined.

  • However, pathophysiology of disease is a major focus of the second-year curriculum.

  • Rheumatoid arthritis (RA) is a significant, chronic disease that afflicts 1% of the general population in most countries [ 1 ] . Joint damage typically occurs before patients are diagnosed, and most of the joint destruction occurs within the first 2 years of diagnosis [ 2 ] . Therapeutic drugs such as sulfasalazine and methotrexate (MTX) only slow the progression of the disease, suggesting that these drugs fail to adequately quell the underlying pathophysiology of RA [ 3 ] .

  • Many surgical reports attempt to determine the best surgical treatment for PFD, yet do not address the pathophysiology.


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