Example sentences for: pathophysiological

How can you use “pathophysiological” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, since SPARC is a matricellular protein involved in cell-matrix interaction [ 3 4 23 ] , cell-matrix interaction-related defects may exert a significant influence in large wounds of SPARC-null mice causing premature loss of a part of the scabs and of the neoepidermis, a pathophysiological process requiring repeated healing.

  • Although we feel it may be premature to speculate on the putative pathophysiological significance of this increase in immunoreactive TNF-α, the fact that TNF-α can induce MMP-9 expression in macrophages [ 47 ] , suggests that TNF-α may play an as yet undetermined role in the mechanism of MMP-9 release observed in our studies.

  • Central pathophysiological features of the disease occur in the synovium, with thickening of the lining layer (or intima) and infiltration of the sublining layer, mainly by macrophages and lymphocytes [ 1 ] . In addition, the fluid-filled joint cavity contains numerous neutrophils, particularly during acute flares of RA [ 2 ] .

  • PCA is one of several types of cancers in which IL-6 has been found or is thought to play a pathophysiological role.

  • Several researchers have also evaluated ibuprofen, and beneficial effects on pathophysiological changes have been observed [ 3 ] . The first major study of ibuprofen in endotoxic shock was performed by Jacobs et al.


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