Example sentences for: pathologies

How can you use “pathologies” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, our results suggest that local expression of TGF-β1, unlike systemic expression, is not therapeutic due to adverse pathologies associated with elevated intra-articular TGF-β1 expression.

  • The interplay between organellar and nuclear genomes accounts for a large part of the diversity in mitochondrial pathologies.

  • "Let's face it, the pathologies are severe in these areas," Jackson said.

  • In summary, in our experiments the in vitro effect of a 1-6 hour exposure to domoic acid on rat neonatal microglia activation and concomitant TNF-α, MMP-9 and O 2 - release was clearly distinct in its magnitude from that observed after exposure to LPS, an agent involved in endotoxic shock and other central nervous pathologies [ 3 ] . Even though this present study was limited to the study of the in vitro effects of domoic acid on three microglia mediators, namely TNF-α, MMP-9 and O 2 -, it provides the first experimental evidence to our knowledge that domoic acid, at in vitro concentrations that are toxic to neuronal cells, can trigger a limited activation of rat neonatal microglia and the concomitant release of modest though statistically significant amounts of TNF-α and MMP-9.

  • A primary defect in oxidative phosphorylation defines class I. Distinct mitochondrial pathologies may overlap more than one class, for example Leigh syndrome (see below).


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