Example sentences for: pathogenicity

How can you use “pathogenicity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, the failure to maintain the resistant virus on subsequent passage suggests that the pathogenicity of 14-P4 may have been only partially attenuated relative to the sensitive virus and indeed the pathogenicity of the clonal virus isolate, 14-P4E, was severely attenuated.

  • Yersinia pestis , the causative agent of bubonic plague, harbors a large virulence plasmid that is essential for pathogenicity.

  • The additional phenotypes now associated with LMNA mutations also favor alternative mechanisms of pathogenicity.

  • Tumor necrosis factor (TNF) has been implicated in the development and pathogenicity of infectious diseases and autoimmune disorders, such as septic shock, arthritis, and hypotension [ 1 2 3 4 ] . It plays a pivotal role in the inflammatory cascade and, together with IL-1 and IL-6, has been shown to mediate the acute-phase response [ 5 6 ] . Confirmation of its significance in disease comes from the success of clinical trials using anti-TNF therapy to treat rheumatoid arthritis and Crohn's disease [ 7 8 9 10 ] .

  • The inability to detect sterilizing immunity in high-dose challenge experiments led to a shift of focus towards indirect effects of vaccine candidates on the pathogenicity of the infection and the infectiousness of the vaccinee.


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