Example sentences for: pathogenesis

How can you use “pathogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This is consistent with the hypothesis that oxidative DNA damage is an important factor in the β-cell failure that plays a role in the pathogenesis of human type 2 diabetes.

  • Further epidemiological studies of Ogg1 expression as well as studies of the expression of other genes and proteins that are involved in DNA damage responses should also be performed to further test the hypothesis that DNA damage is involved in the pathogenesis of type 2 diabetes.

  • Recent work by Hasty and coworkers [ 3] has demonstrated that local expression of IL-1β by articular chondrocytes activates autocrine gene expression, which contributes to the pathogenesis of osteoarthritis (OA).

  • The primary support for the pelvic organs comes from the pelvic floor muscles [ 1 2 ] . This suggests that an alteration to the levator ani supportive function may significantly contribute to the pathogenesis of PFD [ 3 ] , which affect 5% of younger and nearly 50% of elderly women [ 2 ] . In women, the levator muscles form a horizontal shelf with an anterior midline cleft (the urogenital hiatus) through which the urethra, vagina, and rectum pass.

  • Significant portion of these T-lymphocytes are γ/δ-TCR +This subpopulation of lymphocytes has been identified as part of the pathogenesis of autoimmune diseases.


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