Example sentences for: pathogenesis

How can you use “pathogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several studies surrounding the interactions of M. paratuberculosis with macrophages have been published because of its importance in pathogenesis.

  • A candidate gene is usually selected because the gene product might relate to pathogenesis of disease.

  • An inverse correlation between the serum catecholamines and potassium levels suggests that a catecholamine surge following SAH plays an important role in the pathogenesis of hypokalemia during the acute phase of SAH.

  • Long polyglutamine repeats have been found in a number of transcription factors [ 39 ] . Notably, the C-terminus of murine HMG-box protein SRY contains a large polyglutamine repeat region that is responsible for the sex-determining function of this protein [ 40 ] . However, a number of neurodegenerative disorders, such as Huntington disease and spinobulbar muscular atrophy, are also strongly associated with proteins containing a polyglutamine stretch [ 41 ] . Conformational change and protein misfolding in the expanded polyglutamine region is believed to be the molecular basis of the pathogenesis [ 42 ] . Whether the presence of polyglutamine repeats in the C-terminus of human TNRC9 is important for function or alternatively hinders its ability to form a functional protein remains to be determined.

  • [ 4 ] Such epitopes also find application in tetramer staining as powerful immuno-markers for estimating antigen specific T cells during pathogenesis.


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