Words similar to pathogenesis
Example sentences for: pathogenesis
How can you use “pathogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:
3 (63%) was discovered using microdissected foci, suggesting the presence of a putative tumor suppressor gene(s) on 18p with an important role in the pathogenesis of breast cancer.
The apparent lack of response of genital fibroblasts to androgen in vitro , despite expression of a normal AR, has important implications for future research in defining the role of androgen in genital development and the pathogenesis of ambiguous genitalia.
The concept of lung fibroblasts as effector cells in the pathogenesis of idiopathic pulmonary fibrosis (IPF) has recently evolved [ 1 2 ] . Lung fibroblasts respond, in vitro , to inflammatory cytokines by producing growth factors and collagen, resulting in fibroblast proliferation and extracellular matrix deposition [ 2 3 4 ] . In addition, activated lung fibroblasts have been shown to produce large amounts of inflammatory cytokines and chemokines, in vitro , and hence, these cells may also have a role as effector-inflammatory cells [ 1 2 ] . This capacity to produce both inflammatory and fibrotic factors could mean that phenotypically altered lung fibroblasts act simultaneously as effector and target cells, via paracrine and autocrine mechanisms, perpetuating the fibrotic process [ 2 ] .
Despite significant progress towards understanding the pathogenesis of SSc and other fibrotic diseases, effective treatment is still lacking.
Free-radicals ( e.g. , superoxide, hydroxyl radicals, nitric oxide and peroxynitrite) have long been thought to be a key element in the cellular dysfunction and death that are central to the pathogenesis of many aspects of diabetes.
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