Words similar to pathogenesis

Example sentences for: pathogenesis

How can you use “pathogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

This is consistent with the hypothesis that oxidative DNA damage is an important factor in the β-cell failure that plays a role in the pathogenesis of human type 2 diabetes.
The p53 mutant mice tend to develop rhabdomyosarcoma [ 29 ] . P53 is a tumor suppressor regulating cell cycle control and apoptosis, and p53 is one of the many downstream targets of ATM kinase [ 25 27 ] . ATM phosphorylate p53 at Serine 15 in response to DNA damage agents [ 17 ] . It is unknown how the mutated ATM contributes to pathogenesis of rhabdomyosarcoma in the presence of the mutated p53.
Such genetic heterogeneity has been described for multiple loci in breast cancer [ 3, 11, 16, 19, 20], providing an understanding of the complex picture of breast cancer pathogenesis.
Several lines of evidence support the concept that neutrophil elastase contributes to the pathogenesis of emphysema [ 6, 7].
The use of diuretics in the management of ARF remains controversial despite several advances in the understanding of the pathogenesis of renal failure and the mechanisms of action of the agents commonly used to manage it.