Example sentences for: pathways

How can you use “pathways” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This aspect of APP metabolism bears resemblance to the proteolytic signal transduction pathways involved in processing pro-TGFα [35,36] and Notch [44].

  • The MAP kinase pathway consists of 3 major parallel pathways designated as the ERK (p42/44, Extracellular signal-Regulated Kinase), SAPK/JNK (p46, Stress-Activated Protein Kinase/ c-Jun NH2-terminal Kinase) and p38 pathways [ 12 13 14 ] . Activation of each pathway above involves phosphorylation of a number of upstream and downstream family members of the pathway.

  • It is probable, however, that like tumorigenicity suppressor genes and oncogenes many more genes involved in metastasis remain to be discovered since the process is complex, involving a large number of pathways [ 4 ] . Most of the known genetic mechanisms involved in the progression of a tumor to the metastatic state involve the loss of function of genes that prevent cells from becoming invasive.

  • This leads to the formation of adhesions (anterior synechiae) that block aqueous humor access to its drainage pathways including the trabecular meshwork and Schlemm's canal in the iridocorneal angle [ 11, 12].

  • The molecular isolation of these “dwarfing genes” has revealed that they encode components of the GA biosynthesis and response pathways (Peng et al.


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