Words similar to osteoclasts

Example sentences for: osteoclasts

How can you use “osteoclasts” in a sentence? Here are some example sentences to help you improve your vocabulary:

6b), which are features of osteoclasts (OCs).
In vivo and in vitro studies of avian osteoclasts led Pederson et al to suggest that modulation of the Ocl response to estrogen may be controlled by alterations in the Ocl estrogen receptor level [ 3].
Estradiol has been shown to modulate IL-1 action on human osteoclasts in vitro; estrogen administration inhibited IL-1-mediated cytokine (IL-8) mRNA induction and caused increased Ocl apoptosis [ 26].
Osteoclasts are critical for both the continuous remodeling of normal bone tissue as well as the repair of fractured bones [ 2 ] . During normal bone remodeling, osteoclast-mediated bone resorption is balanced by osteoblast-mediated bone formation, resulting in the maintenance of skeletal bone mass.
Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.