Example sentences for: osteoclasts

How can you use “osteoclasts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Future studies designed to understand IFN-γ signaling in mature osteoclasts are needed to resolve this issue.

  • Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.

  • The calcified cartilage is then invaded by blood vessels that bring osteoblasts and osteoclasts, and bone is formed.

  • Less robust cultures with 80-150 osteoclasts per well were more accurately quantitated by counting individual osteoclasts (Fig.

  • Osteoclasts, as well as osteoblasts, possess estrogen receptors [ 3, 4, 5, 6].


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