Words similar to osteoclasts

Example sentences for: osteoclasts

How can you use “osteoclasts” in a sentence? Here are some example sentences to help you improve your vocabulary:

Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.
TRANCE is known to be expressed by activated T cells, and can stimulate dendritic cells and osteoclasts [ 18].
Osteoclasts were large, multinucleated cells, and expressed high levels of tartrate-resistant acid phosphatase (TRAP).
Since it is known that osteoclasts express IFN-γ receptors [ 47 48 ] , it begs the question as to why this pathway remains operant.
Future studies designed to understand IFN-γ signaling in mature osteoclasts are needed to resolve this issue.