Example sentences for: osteoarthritis

How can you use “osteoarthritis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CDDO = 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; DMEM = Dulbecco's modified Eagle's medium; GAPDH = glyceraldehyde-3-phosphate dehydrogenase; IκB = inhibitor of NF-κB; IL = interleukin; MMP = matrix metalloproteinase; OA = osteoarthritis; RA = rheumatoid arthritis; RT-PCR = reverse-transcriptase polymerase chain reaction; TNF-α = tumor necrosis factor-α.

  • Gene transfer of TGF-β1 to the synovium is thus not suitable for treating intra-articular pathologies, such as the repair of damaged cartilage, associated with rheumatoid arthritis and osteoarthritis.

  • For example, a study by Shipley on the treatment of osteoarthritis with the homeopathic remedy Rhus tox reported no difference in outcome compared to placebo.

  • DMEM = Dulbecco's modified Eagle medium; ELISA = enzyme-linked immunosorbent assay; FBS = fetal bovine serum; HSF = human synovial fibroblast; (r/t)IL-1Ra = (recombinant/transgenic) IL-1 receptor antagonist; OA = osteoarthritis; PBS = phosphate-buffered saline; PGE 2 = prostaglandin E 2 ; RA = rheumatoid arthritis.

  • Since TGF-β1 has anti-inflammatory properties as well as being able to stimulate new matrix synthesis by chondrocytes, it represents a possible therapeutic agent with which to treat pathologies associated with rheumatoid arthritis and osteoarthritis by local gene delivery.


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