Words similar to osteoarthritis
Example sentences for: osteoarthritis
How can you use “osteoarthritis” in a sentence? Here are some example sentences to help you improve your vocabulary:
DMEM = Dulbecco's modified Eagle medium; ELISA = enzyme-linked immunosorbent assay; FBS = fetal bovine serum; HSF = human synovial fibroblast; (r/t)IL-1Ra = (recombinant/transgenic) IL-1 receptor antagonist; OA = osteoarthritis; PBS = phosphate-buffered saline; PGE 2 = prostaglandin E 2 ; RA = rheumatoid arthritis.
CDDO = 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; DMEM = Dulbecco's modified Eagle's medium; GAPDH = glyceraldehyde-3-phosphate dehydrogenase; IκB = inhibitor of NF-κB; IL = interleukin; MMP = matrix metalloproteinase; OA = osteoarthritis; RA = rheumatoid arthritis; RT-PCR = reverse-transcriptase polymerase chain reaction; TNF-α = tumor necrosis factor-α.
Gene therapy represents a novel approach for delivery of therapeutic agents to joints in order to treat the pathologies associated with RA and osteoarthritis, as well as other disorders of the joints.
Given that TGF-β1 is able to induce new matrix synthesis from chondrocytes in culture as well as able to block inflammation in vivo , it has been proposed that local intra-articular gene transfer of TGF-β1 could be therapeutic for the treatment of rheumatoid arthritis as well as osteoarthritis.
As a novel approach to therapy, we and other workers have focused on developing the methods for local transfer of genes encoding therapeutic agents to the joint [ 13 14 15 16 17 18 19 ] . This strategy also can be applied to the treatment of osteoarthritis and for aiding the repair of the cartilage and other intra-articular tissues.
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