Example sentences for: osteoarthritis

How can you use “osteoarthritis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • IL-1 has been implicated as a pathogenic mediator in numerous inflammatory and degenerative conditions, including rheumatoid arthritis (RA) and osteoarthritis (OA) [ 1 ] . The IL-1 receptor antagonist (IL-1Ra), a naturally occurring inhibitor of the biologic actions of IL-1, has obvious therapeutic potential in such diseases [ 2 ] ; indeed recombinant human IL-1Ra (anakinra) has recently been approved for use in patients with RA as the drug Kineret™ (Amgen, Inc., Thousand Oaks, CA, USA).

  • Given that TGF-β1 is able to induce new matrix synthesis from chondrocytes in culture as well as able to block inflammation in vivo , it has been proposed that local intra-articular gene transfer of TGF-β1 could be therapeutic for the treatment of rheumatoid arthritis as well as osteoarthritis.

  • An SCL was also established from osteoarthritis synovium (OA5/26) using the same procedure.

  • Gene therapy represents a novel approach for delivery of therapeutic agents to joints in order to treat the pathologies associated with RA and osteoarthritis, as well as other disorders of the joints.

  • Ang = angiopoietin; BSA = bovine serum albumin; FBS = fetal bovine serum; HMVEC = human microvascular endothelial cell; OA= osteoarthritis; PCR = polymerase chain reaction; RA = rheumatoid arthritis; RT-PCR = reverse transcription polymerase chain reaction, SE = standard error; Tie = receptor tyrosine kinase; VEGF = vascular endothelial growth factor.


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