Example sentences for: osteoarthritis

How can you use “osteoarthritis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Recent work by Hasty and coworkers [ 3] has demonstrated that local expression of IL-1β by articular chondrocytes activates autocrine gene expression, which contributes to the pathogenesis of osteoarthritis (OA).

  • Gene therapy represents a novel approach for delivery of therapeutic agents to joints in order to treat the pathologies associated with RA and osteoarthritis, as well as other disorders of the joints.

  • 9 kg/m 2and obese if it was ≥ 30 kg/m 2. Additional BMI data required for comparison purposes were obtained from currently available population-based estimates of BMIs in the American adult population [ 8, 9, 10] and from 110 age-matched patients of both genders without symptomatic hip osteoarthritis who were hospitalized concurrently.

  • AP-1 = activator protein-1; COL2A1 = procollagen 2 alpha 1; egr-1 = early growth response gene-1; ets = erythroblastosis gene twenty-six; IL-1β = interleukin-1β; LH = lactalbumin hydrolysate; LIF = leukemia inhibitory factor; MAPK= mitogen-activated protein kinase; MMP = matrix metalloproteinase; NF-κB = nuclear factor-κB; OA = osteoarthritis; PDGF = platelet-derived growth factor; RT-PCR = reverse transcriptase polymerase chain reaction; SMAD4 = mothers against dpp homolog 4; TGF-β = transforming growth factor-β.

  • To determine which of these angiogenic factors may play a role in RA, we investigated both the distribution and the levels of mRNA for Tie1, Tie2, Ang-1 and Ang-2 in synovial tissue obtained from RA patients, compared with that from subjects with osteoarthritis (OA) and normal tissues.


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