Words similar to osteoclast
Example sentences for: osteoclast
How can you use “osteoclast” in a sentence? Here are some example sentences to help you improve your vocabulary:
Using this technique, we analyzed cytokine (IL-2, IL-4, IL-6, IL-10, IL-13, IFN-γ, TNF-α, and LT-α), activation marker (CD154 [CD40 ligand] and TRANCE - also called receptor activator of nuclear factor-κ B ligand [RANKL] or osteoclast differentiation factor [ODF]), and chemokine receptor expression by individual CD4 +memory T cells isolated from rheumatoid synovium and blood.
7 (RAW cells) or splenic macrophages from CBA/BL6 mice as osteoclast precursors.
In the present study in the mouse, differentiation of osteoclast progenitors appears to be dependent on the direct interaction of bone marrow stromal cells with Ocl precursor cells [ 19, 20].
M-CSF is essential for macrophage maturation, but formation of osteoclasts also requires contact between osteoclast precursors and stromal cells or osteoblasts [ 23].
The dominance of IFN-γ over RANKL, which we observed in vitro (1 ng IFN-γ counteracts 200 ng RANKL when simultaneously administered), probably allows this macrophage activation to occur even in the presence of RANKL expressed on circulating, activated T cells [ 20 40 ] . In the bone microenvironment, however, more abundant RANKL produced by osteoblasts/stromal cells may influence certain monocytes to commit to the osteoclast lineage [ 41 42 ] .