Words similar to osteoclast
Example sentences for: osteoclast
How can you use “osteoclast” in a sentence? Here are some example sentences to help you improve your vocabulary:
These data support the hypothesis that sensitivity to IFN-γ decreases with increasing osteoclast differentiation and that the mechanism by which RANKL and IFN-γ reciprocally inhibit each other in pre-osteoclasts is mediating the irreversible commitment into the osteoclast or activated macrophage lineages.
These effects were irreversible and not caused by inhibition of proximal signaling at the level of STAT1 or TRAF6, suggesting that resistance to IFN-γ is caused by a complex differentiation program specifying the osteoclast fate.
We have demonstrated, using in vitro methods, that osteoclast precursors exposed to RANKL for 1-2 days can be rendered resistant to maximal osteoclast-inhibitory doses of IFN-γ.
Although the role of the osteoclast in bone resorption is becoming better understood [ 1], much remains to be learned about osteoclastogenesis and the exact mechanism of action of anti-resorbing agents on the functional osteoclast.
Hematopoietic cells also influence osteogenic cell differentiation, and some evidence suggests that mature lymphocytes influence osteoclast and osteoblast function.
Loading...