Example sentences for: osteoclast

How can you use “osteoclast” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In addition to osteoclast activation, S. aureus inhibits bone-matrix synthesis, further compounding bone loss observed with osteomyelitis [ 24 ] .

  • These data support the hypothesis that sensitivity to IFN-γ decreases with increasing osteoclast differentiation and that the mechanism by which RANKL and IFN-γ reciprocally inhibit each other in pre-osteoclasts is mediating the irreversible commitment into the osteoclast or activated macrophage lineages.

  • Although the role of the osteoclast in bone resorption is becoming better understood [ 1], much remains to be learned about osteoclastogenesis and the exact mechanism of action of anti-resorbing agents on the functional osteoclast.

  • For cultures utilizing lower levels of RANKL and low osteoclast numbers, densitometric quantitation of TRAP was a more sensitive measure of osteoclastogenesis (Fig.

  • Girasole et al have recently shown that production of IL-6 is inhibited in vitro by exposure of marrow cells to 17β-estradiol; cultures of mouse bone cells showed suppressed osteoclast development when exposed to either 17β-estradiol or a neutralizing antibody to Il-6 [ 31].


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