Words similar to osteoclast
Example sentences for: osteoclast
How can you use “osteoclast” in a sentence? Here are some example sentences to help you improve your vocabulary:
M-CSF is essential for macrophage maturation, but formation of osteoclasts also requires contact between osteoclast precursors and stromal cells or osteoblasts [ 23].
Proper sealing of the osteoclast against the bone surface and a functional brush border are two ultrastructural components believed to be of major importance in Ocl function.
For cultures utilizing lower levels of RANKL and low osteoclast numbers, densitometric quantitation of TRAP was a more sensitive measure of osteoclastogenesis (Fig.
These effects were irreversible and not caused by inhibition of proximal signaling at the level of STAT1 or TRAF6, suggesting that resistance to IFN-γ is caused by a complex differentiation program specifying the osteoclast fate.
The potency of IFN-γ as a macrophage activator and osteoclast inhibitor suggests a prominent role for T cells and/or NK cells in the regulation of bone resorption, as these cells constitute the major source of IFN-γ [ 18 ] . A link between activated T cells and osteoclast inhibition by IFN-γ has been highlighted in a report by Takayanagi et al ., providing the first in vivo evidence that the immune system may influence osteoclastogenesis [ 38 ] . Interestingly, other groups have demonstrated that activated T cells induce osteoclastogenesis via upregulation of surface RANKL, presenting a dilemma regarding the role of activated T cells in osteoclastogenesis [ 20 40 45 ] .
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