Example sentences for: osteoblasts

How can you use “osteoblasts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These results demonstrate that S. aureus is a potent inducer of caspase-8 activation in osteoblasts, equivalent to a known inducer of caspase-8 [ 45 ] . Overall, the levels of caspase-8 enzymatic activity at 2 h were significantly higher compared to the ones obtained 45 min post-infection (data not shown).

  • Marrow stroma includes a subpopulation of undifferentiated cells that are capable of becoming one of a number of phenotypes, including chondrocytes, osteoblasts, adipocytes, fibroblasts, possibly muscle cells, and the reticular cells that support hematopoietic cell differentiation [ 1, 2].

  • Anti-TRAIL antibody was added to the cultures again to neutralize any TRAIL produced by the osteoblasts in response to the infection.

  • Results demonstrate that purified bacterial surface structures and S. aureus extracellular products present outside osteoblasts are not a sufficient stimulus for TRAIL induction, and that physical contact between bacteria and osteoblasts is required for optimal induction of TRAIL expression.

  • We have previously demonstrated that S. aureus induces TRAIL expression in normal human and mouse osteoblasts [ 41 ] . Messenger RNA encoding TRAIL is rapidly and dramatically up-regulated following exposure of osteoblasts to S. aureus . TRAIL mRNA expression is absent in uninfected cultures and shows a dose-dependent response to S. aureus . In contrast to the inducible nature of TRAIL mRNA, the messages encoding death-domain-containing TRAIL receptors are constitutively expressed in human and mouse osteoblasts [ 41 ] . Additionally, TRAIL protein is expressed and secreted following infection of osteoblasts with S. aureus . In contrast, uninfected osteoblasts do not express significant amounts of TRAIL protein.


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