Words similar to osteolysis
Example sentences for: osteolysis
How can you use “osteolysis” in a sentence? Here are some example sentences to help you improve your vocabulary:
The resolution of this issue is further clouded by the apparent contradictory findings that IFN-γ is an extremely potent anti-osteoclastogenic factor [ 38 ] but it can be found at high levels in sites of osteolysis [ 39 ] . To reconcile this controversy we performed a series of experiments aimed at understanding how IFN-γ could induce either bactericidal effects via macrophage activation or osteoclastic bone resorption, by influencing the same progenitor cell in the same bone environment.
Breast cancer cells frequently metastasize to bone causing bone destruction and hypercalcemia [ 9 ] . Parathyroid hormone-related protein (PTHrP), secreted by these cells, is a major mediator of the osteolytic process [ 10 ] . Osteolysis leads to the release of TGFβ which, in turn, further induces PTHrP expression [ 11 ] . Other tumor-relevant genes, such as pai-1 or upa , can also be activated by TGFβ.