Words similar to osteopenia
Example sentences for: osteopenia
How can you use “osteopenia” in a sentence? Here are some example sentences to help you improve your vocabulary:
In particular, LIFR null mutation remains a neonatal lethal with associated osteopenia and an absence of glial cells in late gestation, as described below.
Fragility may be increased in the adrenalectomy group as evidenced by broken mineralized bone at the growth plate, presumably due to osteopenia combined with handling post mortem.
The presence of growth retardation [ 17 ] , osteopenia [ 18 ] , and gastrointestinal abnormalities, however, suggest a potentially important role for MeCP2's function in the peripheral and autonomous nervous system and in other tissues.
Previously, studies of phenotypes in this laboratory have shown that SPARC-null mice develop osteopenia around 2.5 months of age [ 19 ] in bones where SPARC is normally the most abundant non-collagenous glycoprotein [ 3 ] . The second phenotype thus far uncovered is in the lens where SPARC is normally produced by lens epithelial cells [ 20 21 ] and is a component of the lens capsule [ 20 22 ] . SPARC-null mice show progressive cataract formation beginning approximately 1.5 months after birth [ 14 21 ] . Electron microscopy of the SPARC-null lens revealed abnormality at the lens cell-ECM (capsule) interface with an intrusion of cellular processes into the basement membrane of the lens capsule, whereas wild-type lens exhibited a precise border at the cell-matrix interface [ 23 ] . In the present study, we show for the first time that SPARC plays a role in wound repair in vivo and in vitro.
Maternal adrenalectomy worsens the osteopenia, while maternal hormone suppression through RU486 improves the presumed GC related phenotypes: osteopenia, skeletal muscle integrity and glial development.
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