Example sentences for: osteoporosis

How can you use “osteoporosis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a consequence, osteoclast dysregulation leads to osteoporosis (decreased bone mass caused by excess osteoclast activity) or to osteopetrosis (increased bone mass caused by insufficient osteoclast activity).

  • The only bone anabolic agent known to increase bone mineral density in both animal models and clinical settings is human parathyroid hormone 1-34 (PTH), which has recently been approved by the FDA in patients with advance osteoporosis [ 10 ] . Bone-related basic and clinical research has been searching intensively for alternative anabolic agents for the treatment of osteoporosis.

  • This Swiss-Webster outbred mouse strain utilized in this study has proven to be a valuable model for investigating the efficacy of both anabolic and anti-resorptive therapies for the treatment of osteoporosis.

  • Such treatment is readily available, since an estimated 3 million patients in the US alone take statins daily to treat hyperlipidemia with few side effects [ 7 ] . Osteoporosis is increasingly recognized as an eminent public health problem, as the mean age of populations in most Western countries increases and costs related to osteoporosis are expected to grow six-fold by the year 2040 [ 8 ] . Data from the National Health and Nutrition Examination Survey, using a definition of osteoporosis developed by the World Health Organization, estimate that in the United States up to 20% of Caucasian women over 50 have osteoporosis and up to 50% have low bone mass.

  • Progesterone interacts synergistically with estrogen in bone remodeling [ 54 ] , while GC excess is implicated in osteoporosis.


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