Words similar to osteoclastogenesis

Example sentences for: osteoclastogenesis

How can you use “osteoclastogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

While the RANK-RANKL signal is absolutely required for osteoclastogenesis, the efficiency of this process is influenced by cytokines.
With respect to osteoclast formation, IFN-γ is known to potently inhibit RANKL-mediated osteoclastogenesis in both spleen-derived macrophage cultures and bone marrow coculture systems [ 19 20 21 ] . It has also been demonstrated that mice defective in IFN-γ signaling have a more rapid onset of arthritis and bone resorption compared with wild-type mice, suggesting a protective role of IFN-γ in early arthritis [ 21 22 ] .
The bioactivity of GST-RANKL was verified by RAW cell osteoclastogenesis and TRAP expression before experimental use.
It is noteworthy to point out that the dominant/irreversible inhibitory effects of IFN-γ on osteoclastogenesis are fundamentally different to the transient/reversible inhibitory effects of IL-4 on this process, which are mediated by STAT6 inhibition of NFκB activation [ 49 50 ] . In the present article, we demonstrate that RANKL-induced osteoclastogenesis cannot be recovered following exposure to IFN-γ.
IFN-γ potently and irreversibly inhibits RANKL-induced osteoclastogenesis