Example sentences for: osteoclastogenesis

How can you use “osteoclastogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For cultures utilizing lower levels of RANKL and low osteoclast numbers, densitometric quantitation of TRAP was a more sensitive measure of osteoclastogenesis (Fig.

  • In contrast, Wei et al . have demonstrated that pre-osteoclasts do not lose their potential to differentiate into mature osteoclasts following a similar exposure to IL-4 [ 50 ] . It thus appears that IFN-γ anti-osteoclast activity is mediated by inducing terminal differentiation away from the osteoclast lineage, while IL-4 directly interferes with RANKL signaling during osteoclastogenesis.

  • The present results underscore the importance of developing a complete understanding of osteoclastogenesis in vivo with regard to location, time, and the signal transduction pathways involved.

  • The different kinetics between IFN-γ-mediated macrophage activation (<24 hours) and RANKL-medicated osteoclastogenesis (4-5 days) prompted us to investigate the effects of IFN-γ on RANKL-pretreated cells (Fig.

  • Osteoblasts are also known to secrete osteoprotegerin (OPG), which binds TRANCE, thus inhibiting osteoclastogenesis.

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