Words similar to osteoclastogenesis
Example sentences for: osteoclastogenesis
How can you use “osteoclastogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:
For cultures utilizing lower levels of RANKL and low osteoclast numbers, densitometric quantitation of TRAP was a more sensitive measure of osteoclastogenesis (Fig.
The potency of IFN-γ as a macrophage activator and osteoclast inhibitor suggests a prominent role for T cells and/or NK cells in the regulation of bone resorption, as these cells constitute the major source of IFN-γ [ 18 ] . A link between activated T cells and osteoclast inhibition by IFN-γ has been highlighted in a report by Takayanagi et al ., providing the first in vivo evidence that the immune system may influence osteoclastogenesis [ 38 ] . Interestingly, other groups have demonstrated that activated T cells induce osteoclastogenesis via upregulation of surface RANKL, presenting a dilemma regarding the role of activated T cells in osteoclastogenesis [ 20 40 45 ] .
Hofbauer et al suggest that the stimulation of the pool of M-CSF precursors to committed osteoclastogenesis by RANKL may be one of the central pathophysiologic pathways involved in increasing the number of osteoclasts in osteoporosis.
Osteoclasts were counted using three equivalent methods, optimized for the extent of osteoclastogenesis.
In the present study, we demonstrate that early exposure to RANKL renders osteoclast precursors resistant to the effects of IFN-γ, including inhibition of osteoclastogenesis.
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