Example sentences for: ligase

How can you use “ligase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The notion that Siah, a putative ubiquitin ligase, would have other roles in cell signaling is not surprising.

  • In S. cerevisiae, a key event accompanying exit from mitosis is the inactivation of Clb/Cdc28 protein kinase achieved through degradation of Clb and accumulation of the Clb/Cdc28 inhibitor Sic1 (reviewed in [ 1 ] ). Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase and its substrate specific activator Hct1/Cdh1 are required for degradation of Clb2, the major mitotic cyclin in the budding yeast (reviewed in [ 2 ] ). Whereas hct1Δ and sic1Δ cells appear relatively normal,

  • Finally, the nick is sealed by a DNA ligase [ 16 ] . The base-excision pathway is a principal contributor to the amendment of 8-oxoguanine corruptions in DNA [ 29 ] .

  • Genes encoding the two anthranilate synthase subunits ( trpAa and trpAb ) and aryl-CoA ligase ( acl ) surely belong to an operon, as translational coupling is evident from the overlap of start and stop codons (Figure 4).

  • While it appears likely that trpR , aryl-CoA ligase, trpAa and trpAb belong to a common functional unit, the possible roles of the remaining three genes downstream of acl are problematic at the present time.


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