Words similar to ligase
Example sentences for: ligase
How can you use “ligase” in a sentence? Here are some example sentences to help you improve your vocabulary:
In addition to the key roles in E3 ligase activity, RING finger domains have also been shown to be important for regulating subcellular localization of E3s and/or their substrates in a number of cases [ 53 54 55 56 ] . Studies have shown the MDM2 RING finger domain is required to promote nuclear export of p53 and this activity of MDM2 RING finger seems to be coupled with its ability to promote ubiquitination of p53 [ 53 54 55 ] . Rbx1/ROC1, the small RING finger subunit of the SCF E3 complexes, promotes the nuclear accumulation of Cul1, another subunit of the SCF complexes [ 56 ] . These studies have suggested a correlation between the ubiquitination activities of RING fingers and their roles in regulating subcellular localization of the E3 ligases which they are part of.
The reaction was heated to 95°C for 10 seconds, and cooled to 63-68°C for 5-20 minutes, during which time OCP annealed to genomic target and was circularized by ligase.
In particular, one subunit—Csn5—moderates SCF (Skp1–cullin–F box) and other cullin-based E3 ubiquitin ligases by removal of the ubiquitin-like Rub1/Nedd8 molecule from the cullin subunit of the ligase complex.
Because acl is tightly organized with trpAa and trpAb , it seems feasible that anthranilate might be the substrate of acl . An anthranilate-CoA ligase has been described recently in Azoarcus evansii by Schuhle et al . [ 33].
The correlation coefficient between amplified and unamplified samples is slightly higher in the absence of ligase (Table 3), supporting our previous conclusion that ligase is not required for total RNA amplification in cDNA microarray analysis.
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