Words similar to ligand
Example sentences for: ligand
How can you use “ligand” in a sentence? Here are some example sentences to help you improve your vocabulary:
Binding a ligand to a receptor may trigger a complicated sequence of reactions leading to the synthesis of hundreds of dierent molecular species.
Binding was carried out in 250 μl volume of 50 mM Tris HCl buffer, pH 7.4 in the presence of 0.5-1 nM [ 3H]-DPDPE and increasing concentrations (24-32 different concentrations) of unlabeled ligand.
MAdCAM-1 is normally expressed in the gut, and its expression is dramatically amplified during inflammation [ 2 3 ] . The functional significance of increased appearance of MAdCAM-1 in IBD is supported by several reports which show that immunoneutralization of either MAdCAM-1 or its ligand, the α4β7 integrin, attenuate inflammation and mucosal damage in animal models of colitis [ 8 9 10 ] . However, since monoclonal antibodies directed against other ECAMs, particularly VCAM-1, can as well reduce disease activity in colitis models [ 11 12 13 14 ] , the literature suggests that MAdCAM-1 is probably necessary, but insufficient for the maximal penetrance of experimental and probably also clinical IBD.
For example, recent work has shown that at least one large family of Arabidopsis genes encodes a short (80-120 amino acid) protein similar to a secreted polypeptide ligand for a receptor-like kinase that functions in meristems [ 10].
Comparison of the efficacies of the set of agonists in this study to that of the endogenous ligand, met-enkephalin, showed that all were full agonists.
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