Example sentences for: ligands

How can you use “ligands” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Further understanding of LHC assembly requires a better knowledge of the characteristics of the reaction catalyzed by Chl(ide) a oxidase and whether Chl b is restricted to these complexes because LHCP serves as a specific effector of the oxidation of Chl(ide) a or whether the protein simply provides binding sites for Chl b and prevents its conversion back to Chl a [ 45 ] . The latter appears less likely as a specific effect, because similar ligands should occur in other proteins.

  • The screening of the database of over 200,000 ligands took less than 2 days on a Linux cluster of 150 processors.

  • The van der Waals, bond, angle, dihedral, and improper dihedral parameters for all the ligands were adopted from the Hetero-compound Information Centre-Uppsala HIC-Up http://xray.bmc.uu.se/hicup [ 55 ] . The water molecule under the flaps present in all complexes was included in all steps throughout this study except for 1hvr, where the structural water was removed in the preparation of the protease to be docked with the ligand (the ligand of 1hvr, which is a urea-based inhibitor, does not bind a water molecule in this position).

  • Nalorphine, has been previously categorized as a "mixed agonist/antagonist" ligand [ 6 ] . These are ligands that are believed to act as an agonist at κ and as an antagonist at μ opioid receptors.

  • Preliminary reports have linked ligands active at the GABA receptor with SB or other NTDs, including benzodiazepines, alcohol, and zinc [ 7 8 9 10 11 ] . Preliminary work from this laboratory has shown the GABAa receptor agonist muscimol and the GABAb agonist baclofen produce both SB and the Arnold-Chiari malformation, commonly associated with SB [ 12 13 14 ] . VA appears to produce most of its anticonvulsant effects by increasing levels of GABA in the CNS, presumably by inhibiting the enzyme GABA-transaminase (GABA-T).


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