Words similar to ligases
Example sentences for: ligases
How can you use “ligases” in a sentence? Here are some example sentences to help you improve your vocabulary:
Other members of the superfamily include carbamoyl phosphate synthases, cyanophycin synthetases and D-Ala-D-Ala ligases.
Within the past few years, the RING finger motif has emerged as a core structure feature for many ubiquitin ligases (E3s) [ 52 ] . In most cases, RING fingers function as E2 recruiting domains, and by directly interacting with E2s, bring E2s in the vicinity of ubiquitination substrates, which bind to other parts of the RING finger proteins or other subunits of the RING finger protein containing complexes.
Although the molecular signaling mechanisms that transduce the effects of phasic patterns of work activity to modify muscle mass are incompletely understood, recent evidence implicates pathways that include the signaling molecules PI3 kinase, Akt, mTOR, S6K, and ERK, the ubiquitin ligases MAFbx and MuRF1, and transcription factors of the FOX superfamily in the control of both catabolic and anabolic processes [21,22,23,24].
Many RING-finger-containing proteins that may act as ubiquitin ligases under certain conditions have otherwise diverse structures and functions [ 32 ] . It is clear that Siah can act in the ubiquitin pathway, targeting some proteins for proteolysis, under certain circumstances.
Since the substrates of putative SCF Pop1pand SCF Pop2pubiquitin ligases are unknown, we adopted a substrate-independent assay originally described by Lyapina et al . [ 27 ] . For this experiment, we again used the strains harboring genomically integrated Myc epitope-tagged Pop1p or Pop2p in a background deficient in the respective heterooligomerization partner ( Δpop2 pop1-13myc , Δpop1 pop2-13myc strains).
Loading...