Example sentences for: ligase-mediated

How can you use “ligase-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Determination of transcription initiation sites using RNA ligase-mediated rapid amplification of 5' cDNA ends (5' RLM-RACE)

  • Recently a new method for SNP detection from genomic DNA based on DNA ligase-mediated single nucleotide discrimination and signal amplification by Rolling Circle Amplification (RCA) has been described [ 6 7 8 9 10 ] . An oligonucleotide Open Circle Probe (OCP) anneals to the target SNP such that the 5' and 3' ends of the OCP can be ligated together forming a circle topologically linked to the target.


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