Words similar to ligand-binding
Example sentences for: ligand-binding
How can you use “ligand-binding” in a sentence? Here are some example sentences to help you improve your vocabulary:
For instance, coexpression of type II BMPR with either IA or IB BMPR increases ligand-binding affinity and dramatically enhances biologic activity [ 11].
In three of these cell lines, LNCaP, MDA PCa 2a and MDA PCa 2b, mutations in the ligand-binding domain of the AR confer broad steroid-binding affinity [ 8, 9].
Gene fusions characteristically bring together proteins that function in a concerted manner, such as successive enzymes in metabolic pathways, enzymes and the domains involved in their regulation, or DNA-binding domains and ligand-binding domains in prokaryotic transcriptional regulators [ 1, 2, 3].
The interaction of mammalian growth hormone, prolactin, and vascular endothelial growth factor with their respective extracellular ligand-binding proteins have been observed using yeast two-hybrid sytems [ 10 11 12 13 ] .
These include the PAS-like fold, which is the scaffold of the PAS [ 11 12 ] , GAF [ 13 ] , and probably the CACHE [ 14 ] superfamilies, and the ACT-like fold, which is seen in ACT, ferredoxin and related ligand-binding domains [ 4 15 ] . Identification of such conserved domains has, often, improved our understanding of the general structural and biochemical features that underlie protein-small molecule interactions.