Words similar to ligand-dependent

Example sentences for: ligand-dependent

How can you use “ligand-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

In other cases, however, the balance of coactivator and corepressor recruitment is regulated by direct competition for the AF-2 surface, rather than ligand-dependent coregulator exchange.
The CR-II domain plays an essential role in the ability of TAF II 135 to potentiate ligand-dependent transactivation by the the receptor for all-trans retinoic acid (RAR) in transfected mammalian cells [ 5, 33].
For example, it is possible that the inhibitory effect of LG1069 in the stable CAR expressing cell line is based on the sequestration of limiting amounts of RXR into ligand-dependent homodimers, as has been suggested in previous studies using primary hepatocytes [ 17 ] . However, similar effects were observed with the relatively large amounts of RXR used for the biochemical studies or with the transient transfections, which relied on cotransfected RXR.
No significant change in the extent of ligand-dependent activation was observed following pre-incubation (data not shown).
This receptor has previously been shown to elevate intracellular Ca 2+and activate CamKII in a ligand-dependent manner [ 6 37 38 ] . C57mg cells stably transformed with Rfz-2/β 2 AR retrovirus or wt C57mg cells were treated overnight with propranolol, a β 2 AR antagonist, to maintain the chimeric receptors in an inactivated state.