Words similar to ligand-dependent

Example sentences for: ligand-dependent

How can you use “ligand-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

No significant change in the extent of ligand-dependent activation was observed following pre-incubation (data not shown).
For example, it is possible that the inhibitory effect of LG1069 in the stable CAR expressing cell line is based on the sequestration of limiting amounts of RXR into ligand-dependent homodimers, as has been suggested in previous studies using primary hepatocytes [ 17 ] . However, similar effects were observed with the relatively large amounts of RXR used for the biochemical studies or with the transient transfections, which relied on cotransfected RXR.
In other cases, however, the balance of coactivator and corepressor recruitment is regulated by direct competition for the AF-2 surface, rather than ligand-dependent coregulator exchange.
This receptor has previously been shown to elevate intracellular Ca 2+and activate CamKII in a ligand-dependent manner [ 6 37 38 ] . C57mg cells stably transformed with Rfz-2/β 2 AR retrovirus or wt C57mg cells were treated overnight with propranolol, a β 2 AR antagonist, to maintain the chimeric receptors in an inactivated state.
Upon addition of 1 μM dexamethasone (Dex) the receptor is translocated into the nucleus within 10 min [ 48 ] . When GR-GFP was co-expressed with the wild-type Rab24 in NIH3T3 cells, we observed normal ligand-dependent translocation of GR-GFP into the nucleus when Dex was applied (Fig.