Words similar to ach
Example sentences for: ach
How can you use “ach” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the center of this region is a critical glycine residue that is thought to play a role in establishing a hairpin loop [ 12 ] . Recent x-ray crystallographic data obtained from an ACh binding protein (AChBP) shows a loop structure in this region resulting from a 3 residue turn containing a glycine homologous to G147 of the 5-HT 3 R. On either side of this putative turn region are residues that have been identified as important to receptor binding [ 12 13 14 15 16 17 18 ] . The formation of this loop structure brings amino acids on either side of glycine into close proximity and may form a binding pocket that will accommodate one or more functional groups.
For example, despite the fact that insulin did not inhibit Ach receptor signaling in our experiment, the rat M1 Ach receptor contains several MAP kinase sites, including one Thr-Pro sequence in the 2 ndintracellular loop and 3 Ser-Pro and one Thr-Pro in the 3 rdintracellular loop.
Transfection of PLD1 into SN56 cells resulted in increased PLD activity and ACh production suggesting that PLD1, like PLD2, could potentially be used to supply choline for ACh synthesis.
There are multiple neurotransmitters whose receptors are coupled to PKC-dependent activation of PLD [ 7 ] , and thus this mode of regulating the availability of choline for ACh synthesis is likely to be widespread.
Studies of alert monkeys suggest that the effectiveness of alerting produced by a warning signal can be eliminated by drugs that block noradrenaline [ 7 ] . Lesions of the cholinergic system [ 8 ] and of drugs blocking ACh transmission have effects on orienting of visual attention in monkeys [ 9 ] . The executive network involves dopamine rich areas of the prefrontal cortex and anterior cingulate.
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