Words similar to achr
Example sentences for: achr
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AChR Nicotinic acetylcholine receptor
These effects on colocalization appear to be additive, as did the overall stimulation of AChR expression (Figure 2A).
Mutagenesis studies have identified the interaction of amino acids W89 and R91 in the binding of 5-HT 3 R ligands [ 24 23 ] . Studies conducted in our laboratory have identified three additional putative binding site residues (Y140, Y142, and Y152) [ 25 ] . W89 and R91 are present in a conserved region of LGIC receptors often referred to as loop D [ 24 26 ] . Similarly, Y140, Y142 and Y152 are located in the region homologus to E loop region of nicotinic AchR.
Taken together these observations have led to the hypothesis that LN1 serves as a secondary or supporting stimulus for agrin induced AChR aggregation [ 1 2 24 ] . The present study is directed at a quantitative examination of the interaction between the signal transduction pathways for agrin and LN1 induction of AChR aggregates and colocalized α-DG aggregates.
This is the reverse of the finding for AChR aggregates (Figure 2B).