Words similar to achrs
Example sentences for: achrs
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α-DG aggregate size follows a similar pattern of increase by LN1 (alone or in combination) but not agrin (Figure 4C), but in this case it is the same as the finding with AChRs (Figure 2C).
Again in agreement with AChR observations, α-DG aggregate density is increased by LN1 but not agrin (Figure 4D) - however in this case it appears that this increase is prevented by agrin, while in the case of AChRs the combination follows the LN1 alone phenotype of increased aggregate density.
Also, while laminin stimulation increased the colocalization of AChRs and αDG in our experiments, agrin also produced a similar increase (Figure 5).
Accordingly the question arises as to how this approach can be compared with previous studies which demonstrate a visible colocalization of AChRs and α-DG in muscle cells stimulated by nerve terminals [ 19 ] or agrin [ 4 20 26 27 ] . First we note that the present results do support a significant colocalization of the two molecules in agrin stimulated cells as compared to controls (Figure 5), in general agreement with previous findings.
That the correlation coefficient never approaches unity is also consistent with the previous work - in general it has been found that AChR aggregates contain α-DG, but visible concentrations of α-DG can be found in the absence of AChRs.