Example sentences for: achrs

How can you use “achrs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Again in agreement with AChR observations, α-DG aggregate density is increased by LN1 but not agrin (Figure 4D) - however in this case it appears that this increase is prevented by agrin, while in the case of AChRs the combination follows the LN1 alone phenotype of increased aggregate density.

  • Because of various lines of evidence connecting α-DG to receptor aggregation and to differences in agrin and LN1 pathways of induction, we next examined the effects of the stimulus protocols on cells double labeled for AChRs (fluorescein) and α-DG (rhodamine) to examine the extent of correlation between the labels (see below) and the α-DG distributions.

  • AChRs were labeled with rhodamine (single label experiments) or fluorescein (double label experiments) conjugated αBGT (300 nM, Molecular Probes, T-1175/T-1176), and α-DG with a monoclonal antibody (1:1000, Upstate Biotechnology, 05-298, 45 minutes) followed by a secondary antibody (Rhodamine-Goat anti-mouse IgG, 1:100, Jackson Immuno Research Laboratories, 115-025-003, 45 minutes).

  • α-DG aggregate size follows a similar pattern of increase by LN1 (alone or in combination) but not agrin (Figure 4C), but in this case it is the same as the finding with AChRs (Figure 2C).

  • Accordingly the question arises as to how this approach can be compared with previous studies which demonstrate a visible colocalization of AChRs and α-DG in muscle cells stimulated by nerve terminals [ 19 ] or agrin [ 4 20 26 27 ] . First we note that the present results do support a significant colocalization of the two molecules in agrin stimulated cells as compared to controls (Figure 5), in general agreement with previous findings.


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