Example sentences for: achbp

How can you use “achbp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • R91, E106, F107, W183 and several residues adjacent to the M1 region have all been demonstrated to alter the action of 5-HT and/or m CPBG [ 20 21 25 26 ] . Within the crystal structure of the AChBP, homologous residues are located in the apparent binding site [ 24 ] . The effects of agonist on the 5-HT 3 R are mediated by their interaction with these binding site residues, resulting in stable receptor conformations, including the channel open state.

  • Low-energy conformations were found only in the absence of water molecule, and the calculated binding energies (Table 1- bottom) suggest that HEPES is a poor ligand for nAChRs, and AChBP, and was observed in the crystal structure because of its high concentration (100 mM) in the crystallization condition [ 6 ] .

  • In addition, our data support the existence of a loop structure in this region as has been hypothesized for the nAChR and identified in a homologous AChBP [ 12 23 24 ] .

  • and shown for the AChBP is present in the 5-HT 3 R, then Y140, Y142 and Y152 would be present on the same side of the sheet and all three would be capable of extending into the binding site.

  • For each nAChR dimer, two monomer sequences were threaded onto two consecutive subunits of the AChBP crystal structure, based on the multiple sequence alignment, and the energy of the system was locally minimized by the ICM method [ 10 18 ] . The orientation of all polar hydrogens was systematically optimized through conformational space search combined with local minimization.


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