Words similar to achbp

Example sentences for: achbp

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In addition, our data support the existence of a loop structure in this region as has been hypothesized for the nAChR and identified in a homologous AChBP [ 12 23 24 ] .
For example, amino acids homologous to Y142 and W183 (R104 and W143 respectively) are in close proximity in the AChBP, although on complementary faces of the receptor subunits [ 24 ] . Spier et.
To address further the specificity of this ligand candidate, we docked it, as previously described, to the other three nAChRs subtypes studied in this work, as well as to the crystal structure of AChBP, and calculated the corresponding binding energies (Table 1bottom).
All nAChR residues within 7A of the putative AChBP binding pocket described by Brejc et al.
Previous reports have shown on other systems that a single-residue mutation in a receptor is sufficient for the development of specific ligands [ 13 14 ] . Based on the recent crystal structure of AChBP, we could propose a detailed description of the structural variations of nAChR subtypes.