Words similar to acetylcholine

Example sentences for: acetylcholine

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This orientation of an amino group interacting with an aromatic amino acid in a cation-π interaction has been shown for the nicotinic acetylcholine receptor and has been hypothesized for many LGIC receptors [ 28 29 30 26 ] . This conclusion is based on both the magnitude of the change observed on the wild type receptor for removal of the amino group (400 fold) compared to the effect of the Y142A mutation on lerisetron binding (160 fold) and the lack of any major change in K i for analog 2 as a result of this mutation.
Both acetylcholine and nicotine were docked to our model of the alpha4-beta2 dimer interface.
Surprisingly, the ester moiety of acetylcholine does not seem to interact with the cys-loop of the receptor, as previously suggested by photoaffinity labeling [ 12 ] , but is engaged in similar type of interaction as that observed with the acidic group of HEPES in the AChBP crystal structure [ 6 ] . It is possible that the reactive di-azo group of the photosensitive agonist used in photoaffinity labeling would extend towards the cys-loop, while the conformation of the bound agonist remains in agreement with our model.
Distribution of nicotinic acetylcholine receptor immunoreactivity
AChR Nicotinic acetylcholine receptor