Example sentences for: acetylcholine

How can you use “acetylcholine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Nicotinic acetylcholine receptors (nAChRs) are ion channels threaded through cell membranes.

  • It is now conventional wisdom that acetylcholine and nicotine act at these receptors to alter electrochemical properties at a variety of synapses, which can in turn affect the release of several other neurotransmitters.

  • A formal charge of +1 was assigned to the quaternary ammonium group of acetylcholine and protonated nicotine.

  • Recently, Sixma and colleagues have determined the first high-resolution structure of a soluble acetylcholine binding protein (AChBP), extracted from snail neurons, and homologous to the ligand binding domain of nAChR [ 6 ] . Based on this high-resolution crystal structure, we have built an atomic model of the agonist binding site of nAChR, and docked acetylcholine and nicotine to different receptor isotypes.

  • Acetylcholine fits tightly into the agonist binding site at the alpha4-beta2 interface of nAChR (Figure 2).


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