Example sentences for: acetylcholine

How can you use “acetylcholine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 3) It displays an amide group that occupies a cavity not filled by nicotine or acetylcholine, and makes a network of hydrogen bonds with the indole nitrogen of alpha4-Trp182, the backbone carbonyl of beta2-Ser133 and beta2-Phe144, and with the backbone nitrogen of beta2-Leu146 (Figure 5B).

  • Similarly, acetylcholine and nicotine were docked into the agonist binding site at the alpha3-beta2, alpha4-beta4 and alpha7-alpha7 interfaces.

  • This putative association is strengthened by finding for the first time that targeting of RIα requires the AKAP binding surface [ 17 ] . Yotiao is another AKAP enriched at the NMJ, but appears to bind only RII [ 30 ] . PKA phosphorylates the nAChR when stimulated at the synapse by the neuropeptide CGRP and by adenosine from muscle responding to acetylcholine [reviewed by [ 31 ] ]. This phosphorylation may regulate the degradation of the nAChR [ 32 ] . Consistent with the action at the presynapse, it was shown that PKA facilitation of acetylcholine release is dependent on nerve endplate calcium concentration [ 33 ] . Based on our observation of colocalization with synaptophysin at presynaptic vesicles, RIα may be the isotype that influences this release of neurotransmitter.

  • Acetylcholine receptor aggregation

  • Classical neurotransmitter receptors such as muscarinic acetylcholine receptors (mAChR), adrenergic, dopaminergic, serotoninergic as well as neuropeptide receptors belong to this family ( 1).


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