Words similar to acetylation
Example sentences for: acetylation
How can you use “acetylation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Recent studies demonstrated acetylation of p53 in the C-terminal domain increased the DNA-binding capacity of the protein [ 53, 54, 55].
The characterization of potentially altered interactions between hypophosphorylated RARα and its cofactors will provide unique insight into how post-translational modification of nuclear hormone receptors regulates repressor release, coactivator recruitment, histone acetylation, and transcriptional activation.
RAR/RXR binding to nuclear receptor corepressors such as NCoR and SMRT in the absence of ligand inhibits activation of RA responsive genes [ 3 4 ] . Ligand binding displaces the repressors and recruits coactivator proteins such as CBP which have histone acetyltransferase activity [ 5 ] . Histone acetylation allows for chromatin unwinding and transcriptional initiation of target gene expression [ 6 ] .
Protein and acetylation levels of histone H3 and H4 isoforms on histone samples isolated from SAHA treated and untreated TM10 and TM2H cells stained by Coomassie Brilliant Blue (Fig.
It is noteworthy that the mechanism of SAHA in G1 cell growth arrest may target the expression of specific proteins involved in DNA synthesis as it inhibited E2F-1 and PCNA, but not E2F-4, suggesting that SAHA may cause different levels of histone acetylation at distinct regions of the genome.
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