Example sentences for: acetylation

How can you use “acetylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • RAR/RXR binding to nuclear receptor corepressors such as NCoR and SMRT in the absence of ligand inhibits activation of RA responsive genes [ 3 4 ] . Ligand binding displaces the repressors and recruits coactivator proteins such as CBP which have histone acetyltransferase activity [ 5 ] . Histone acetylation allows for chromatin unwinding and transcriptional initiation of target gene expression [ 6 ] .

  • Whereas the phosphorylation of CDK9 strengthens this complex [16], the acetylation of the lysine at position 50 in Tat weakens it [17].

  • The increases in protein and acetylation levels of H3 and H4 in SAHA treated TM10 and TM2H cell lines were indicated by the strong staining with the acetylation specific antibodies of H3 and H4, while the acetylated slow migrated isoforms showed smearing due to the increases in their protein level (Fig.

  • As SAHA treatment increased histone (H3 and H4) protein and acetylation levels in both cell lines, this may have altered the association of histones with DNA, thereby altering nucleosomal conformation and stability [ 27, 44].

  • It is not known whether SAHA alters the protein acetylation levels of various histones in the mammary epithelial cells.


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