Example sentences for: acetylation

How can you use “acetylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, p53's DNA binding activity is increased by the DNA damage-induced acetylation of the C-terminal of p53 [ 16, 19], and this acetylation requires the prior phosphorylation of the N-terminal of p53 [ 16].

  • Whereas the phosphorylation of CDK9 strengthens this complex [16], the acetylation of the lysine at position 50 in Tat weakens it [17].

  • We focused on H3 and H4 because antibodies are available and acetylation events in those histones have been studied.

  • It is not known at this point whether specific mutations of p53 alter the degree of histone acetylation in cells.

  • SAHA was able to increase histone H3 and H4 protein and acetylation levels, and caused a profound decrease in the protein levels of key molecules, PCNA and E2F-1, essential for DNA synthesis.


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