Example sentences for: acetylation

How can you use “acetylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Fourth, MeCP2 action on chromatin, as suggested by observed changes in histone acetylation [ 31 32 ] , may not involve protein coding genes that are represented on microarrays, but instead, may affect centromeric heterochromatin or the expression of small non-coding RNAs that are abundant in normal brain [ 33 ] . The results presented in this paper contradict the established model of MeCP2 function and necessitate a rethinking of strategies to unravel the pathologic process that leads to neuronal dysfunction in Rett syndrome.

  • It is not known whether SAHA alters the protein acetylation levels of various histones in the mammary epithelial cells.

  • We identified a novel mechanism for SAHA in cell growth arrest through inhibition in DNA synthesis, concomitant with significant increases in the nuclear localization of pRb-2/p130 associated with E2F-4, decreases in key molecules in DNA synthesis (E2F-1, PCNA and p21), and increases in histone H3 and H4 protein and acetylation levels.

  • For example, p53's DNA binding activity is increased by the DNA damage-induced acetylation of the C-terminal of p53 [ 16, 19], and this acetylation requires the prior phosphorylation of the N-terminal of p53 [ 16].

  • We did not, however, observe differences in the initial acetylation levels between untreated TM10 and TM2H cell lines.


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