Example sentences for: acetylation

How can you use “acetylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Fourth, MeCP2 action on chromatin, as suggested by observed changes in histone acetylation [ 31 32 ] , may not involve protein coding genes that are represented on microarrays, but instead, may affect centromeric heterochromatin or the expression of small non-coding RNAs that are abundant in normal brain [ 33 ] . The results presented in this paper contradict the established model of MeCP2 function and necessitate a rethinking of strategies to unravel the pathologic process that leads to neuronal dysfunction in Rett syndrome.

  • Local perturbations of chromatin structure can specifically affect the accessibility and/or function of transcriptional regulatory proteins that bind DNA sequences in the region where histone acetylation or deacetylation took place [ 44].

  • It is not known whether SAHA alters the protein acetylation levels of various histones in the mammary epithelial cells.

  • As SAHA treatment increased histone (H3 and H4) protein and acetylation levels in both cell lines, this may have altered the association of histones with DNA, thereby altering nucleosomal conformation and stability [ 27, 44].

  • Protein and acetylation levels of histone H3 and H4 isoforms on histone samples isolated from SAHA treated and untreated TM10 and TM2H cells stained by Coomassie Brilliant Blue (Fig.


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