Example sentences for: tnf

How can you use “tnf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, TNF supplementation was unable to rescue the abnormal SN50 phenotype.

  • Previous experiments have shown that gene transfer of IL-10 and IL-1 and TNF inhibitors at the time of disease initiation (day 28) is therapeutic.

  • This correlates with the greater extent of Hyal-2 enhancement of TNF killing compared to Hyal-1.

  • This is not a TNF-dependent effect, since the phenotype is not affected by the removal of either TNFR-1 or -2 or by the addition of TNF antibody [ 27 ] . Recent studies have suggested a potential interaction between TTP and both IL-3 and IL-8 via the ARE in their mRNA [ 29 30 ] .

  • While TNFα binds equally well to both receptors, the majority of biologic responses attributed to TNF are mediated via TNFR1 although there is evidence that activation of TNFR2 is responsible for some adverse effects of TNFα [ 19 20 21 22 23 24 ] . Thus, the differential regulation of these two receptors may require drugs that specifically target either TNFR1 or TNFR2 allowing therapeutic efficacy without the expected toxicity profile.


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