Words similar to tnf-induced
Example sentences for: tnf-induced
How can you use “tnf-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:
In this study, using ribozyme technology, we demonstrate an association of decreased expression and function of the M6P/IGF2R with increased cell proliferation and decreased susceptibility to TNF-induced apoptosis in human breast cancer MCF-7 cells.
Preliminary studies on TNF-induced IκBα phosphorylation determined the optimum concentration for inhibition with infliximab.
Our results also showed that M6P/IGF2R down-regulation resulted in decreased sensitivity of MCF-7 cells to TNF-induced apoptosis.
Fletcher et al [ 3 ] also reported that TNF-induced mortality could be reduced by using ibuprofen.
Recent evidence suggests that lysosomal enzymes, such as cathepsins B and D contribute to TNF-induced apoptosis in vitro [ 35 36 37 38 ] and in vivo [ 39 ] . The M6P/IGF2 receptor has been shown to be involved in binding, transport and activation of lysosomal enzymes, including cathepsins [ 12 13 ] . Therefore, it is possible that down-regulation of the M6P/IGF2R results in improper trafficking and activation of cathepsins.